7BBD

Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2

Summary for 7BBD

Entry DOI	10.2210/pdb7bbd/pdb
Descriptor	Polyubiquitin-B,E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 variant 2, ... (6 entities in total)
Functional Keywords	e3 ubiquitin ligase, e2 conjugating enzyme, ubiquitin chain elongation, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	61198.92
Authors	Kiss, L.,Neuhaus, D.,James, L.C. (deposition date: 2020-12-17, release date: 2021-01-27, Last modification date: 2024-01-31)
Primary citation	Kiss, L.,Clift, D.,Renner, N.,Neuhaus, D.,James, L.C. RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination. Nat Commun, 12:1220-1220, 2021 Cited by PubMed: 33619271 DOI: 10.1038/s41467-021-21443-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation