6ZP4
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2
This is a non-PDB format compatible entry.
Summary for 6ZP4
Entry DOI | 10.2210/pdb6zp4/pdb |
EMDB information | 11276 11335 |
Descriptor | 40S ribosomal protein SA, 40S ribosomal protein S9, 40S ribosomal protein S11, ... (57 entities in total) |
Functional Keywords | translational inhibition, sars-cov-2, immune evasion, human ribosome, viral protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 54 |
Total formula weight | 2160440.53 |
Authors | Thoms, M.,Buschauer, R.,Ameismeier, M.,Denk, T.,Kratzat, H.,Mackens-Kiani, T.,Cheng, J.,Berninghausen, O.,Becker, T.,Beckmann, R. (deposition date: 2020-07-08, release date: 2020-07-29, Last modification date: 2020-09-16) |
Primary citation | Thoms, M.,Buschauer, R.,Ameismeier, M.,Koepke, L.,Denk, T.,Hirschenberger, M.,Kratzat, H.,Hayn, M.,Mackens-Kiani, T.,Cheng, J.,Straub, J.H.,Sturzel, C.M.,Frohlich, T.,Berninghausen, O.,Becker, T.,Kirchhoff, F.,Sparrer, K.M.J.,Beckmann, R. Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369:1249-1255, 2020 Cited by PubMed: 32680882DOI: 10.1126/science.abc8665 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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