7ABG

Human pre-Bact-1 spliceosome

This is a non-PDB format compatible entry.

Summary for 7ABG

• Entry DOI: 10.2210/pdb7abg/pdb
• Related: 7AAV 7ABF 7ABH 7ABI
• EMDB information: 11693 11694 11695 11696 11697
• Descriptor: Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, U5 snRNA, ... (55 entities in total)
• Functional Keywords: complex, spliceosome, catalytic activation, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 58
• Total formula weight: 2762070.75

Authors

Townsend, C.,Kastner, B.,Leelaram, M.N.,Bertram, K.,Stark, H.,Luehrmann, R. (deposition date: 2020-09-07, release date: 2020-12-23, Last modification date: 2020-12-30)

• Primary citation: Townsend, C.,Leelaram, M.N.,Agafonov, D.E.,Dybkov, O.,Will, C.L.,Bertram, K.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R.; Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.; Science, 370:-, 2020; PubMed: 33243851; DOI: 10.1126/science.abc3753

Experimental method

ELECTRON MICROSCOPY (7.8 Å)