7ABG

Human pre-Bact-1 spliceosome

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0000398	biological_process	mRNA splicing, via spliceosome
0	0003723	molecular_function	RNA binding
0	0003729	molecular_function	mRNA binding
0	0005515	molecular_function	protein binding
0	0005634	cellular_component	nucleus
0	0005654	cellular_component	nucleoplasm
0	0005681	cellular_component	spliceosomal complex
0	0006397	biological_process	mRNA processing
0	0008380	biological_process	RNA splicing
0	0010468	biological_process	regulation of gene expression
0	0031047	biological_process	regulatory ncRNA-mediated gene silencing
0	0035196	biological_process	miRNA processing
0	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
0	0048255	biological_process	mRNA stabilization
0	0071005	cellular_component	U2-type precatalytic spliceosome
0	0140416	molecular_function	transcription regulator inhibitor activity
0	1903241	biological_process	U2-type prespliceosome assembly
4	0000375	biological_process	RNA splicing, via transesterification reactions
4	0000387	biological_process	spliceosomal snRNP assembly
4	0000389	biological_process	mRNA 3'-splice site recognition
4	0000398	biological_process	mRNA splicing, via spliceosome
4	0003676	molecular_function	nucleic acid binding
4	0003723	molecular_function	RNA binding
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005654	cellular_component	nucleoplasm
4	0005681	cellular_component	spliceosomal complex
4	0005684	cellular_component	U2-type spliceosomal complex
4	0005686	cellular_component	U2 snRNP
4	0006397	biological_process	mRNA processing
4	0008270	molecular_function	zinc ion binding
4	0008380	biological_process	RNA splicing
4	0016607	cellular_component	nuclear speck
4	0046872	molecular_function	metal ion binding
4	0071005	cellular_component	U2-type precatalytic spliceosome
4	0071013	cellular_component	catalytic step 2 spliceosome
4	1903241	biological_process	U2-type prespliceosome assembly
9	0000244	biological_process	spliceosomal tri-snRNP complex assembly
9	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
9	0000387	biological_process	spliceosomal snRNP assembly
9	0000398	biological_process	mRNA splicing, via spliceosome
9	0000932	cellular_component	P-body
9	0003723	molecular_function	RNA binding
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005681	cellular_component	spliceosomal complex
9	0005688	cellular_component	U6 snRNP
9	0005737	cellular_component	cytoplasm
9	0005829	cellular_component	cytosol
9	0006397	biological_process	mRNA processing
9	0008380	biological_process	RNA splicing
9	0030629	molecular_function	U6 snRNA 3'-end binding
9	0033962	biological_process	P-body assembly
9	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
9	0071005	cellular_component	U2-type precatalytic spliceosome
9	0071011	cellular_component	precatalytic spliceosome
9	0071013	cellular_component	catalytic step 2 spliceosome
9	0120115	cellular_component	Lsm2-8 complex
9	1990726	cellular_component	Lsm1-7-Pat1 complex
9	1990904	cellular_component	ribonucleoprotein complex
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000387	biological_process	spliceosomal snRNP assembly
A	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0016020	cellular_component	membrane
A	0016607	cellular_component	nuclear speck
A	0017070	molecular_function	U6 snRNA binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
A	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0097157	molecular_function	pre-mRNA intronic binding
A	0140492	molecular_function	metal-dependent deubiquitinase activity
A	1990904	cellular_component	ribonucleoprotein complex
A1	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
A1	0000339	molecular_function	RNA cap binding
A1	0000340	molecular_function	RNA 7-methylguanosine cap binding
A1	0000380	biological_process	alternative mRNA splicing, via spliceosome
A1	0000398	biological_process	mRNA splicing, via spliceosome
A1	0002191	biological_process	cap-dependent translational initiation
A1	0003676	molecular_function	nucleic acid binding
A1	0003677	molecular_function	DNA binding
A1	0003723	molecular_function	RNA binding
A1	0003729	molecular_function	mRNA binding
A1	0005515	molecular_function	protein binding
A1	0005634	cellular_component	nucleus
A1	0005654	cellular_component	nucleoplasm
A1	0005737	cellular_component	cytoplasm
A1	0005829	cellular_component	cytosol
A1	0005846	cellular_component	nuclear cap binding complex
A1	0006397	biological_process	mRNA processing
A1	0006406	biological_process	mRNA export from nucleus
A1	0006408	biological_process	snRNA export from nucleus
A1	0006417	biological_process	regulation of translation
A1	0006446	biological_process	regulation of translational initiation
A1	0008334	biological_process	histone mRNA metabolic process
A1	0008380	biological_process	RNA splicing
A1	0016071	biological_process	mRNA metabolic process
A1	0017069	molecular_function	snRNA binding
A1	0031047	biological_process	regulatory ncRNA-mediated gene silencing
A1	0031053	biological_process	primary miRNA processing
A1	0031124	biological_process	mRNA 3'-end processing
A1	0031442	biological_process	positive regulation of mRNA 3'-end processing
A1	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
A1	0034518	cellular_component	RNA cap binding complex
A1	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
A1	0035195	biological_process	miRNA-mediated post-transcriptional gene silencing
A1	0042789	biological_process	mRNA transcription by RNA polymerase II
A1	0045292	biological_process	mRNA cis splicing, via spliceosome
A1	0046833	biological_process	positive regulation of RNA export from nucleus
A1	0051028	biological_process	mRNA transport
A2	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A2	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
A2	0000387	biological_process	spliceosomal snRNP assembly
A2	0000398	biological_process	mRNA splicing, via spliceosome
A2	0000956	biological_process	nuclear-transcribed mRNA catabolic process
A2	0003723	molecular_function	RNA binding
A2	0005515	molecular_function	protein binding
A2	0005634	cellular_component	nucleus
A2	0005654	cellular_component	nucleoplasm
A2	0005681	cellular_component	spliceosomal complex
A2	0005688	cellular_component	U6 snRNP
A2	0005689	cellular_component	U12-type spliceosomal complex
A2	0005737	cellular_component	cytoplasm
A2	0005829	cellular_component	cytosol
A2	0006397	biological_process	mRNA processing
A2	0008380	biological_process	RNA splicing
A2	0017070	molecular_function	U6 snRNA binding
A2	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A2	0071004	cellular_component	U2-type prespliceosome
A2	0071005	cellular_component	U2-type precatalytic spliceosome
A2	0071013	cellular_component	catalytic step 2 spliceosome
A2	0097526	cellular_component	spliceosomal tri-snRNP complex
A2	0120115	cellular_component	Lsm2-8 complex
A2	1990726	cellular_component	Lsm1-7-Pat1 complex
A2	1990904	cellular_component	ribonucleoprotein complex
A3	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A3	0000387	biological_process	spliceosomal snRNP assembly
A3	0000398	biological_process	mRNA splicing, via spliceosome
A3	0003723	molecular_function	RNA binding
A3	0003729	molecular_function	mRNA binding
A3	0005515	molecular_function	protein binding
A3	0005634	cellular_component	nucleus
A3	0005654	cellular_component	nucleoplasm
A3	0005681	cellular_component	spliceosomal complex
A3	0005688	cellular_component	U6 snRNP
A3	0006397	biological_process	mRNA processing
A3	0008380	biological_process	RNA splicing
A3	0017070	molecular_function	U6 snRNA binding
A3	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A3	0071005	cellular_component	U2-type precatalytic spliceosome
A3	0071011	cellular_component	precatalytic spliceosome
A3	0120115	cellular_component	Lsm2-8 complex
A3	1990904	cellular_component	ribonucleoprotein complex
A4	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A4	0003711	molecular_function	transcription elongation factor activity
A4	0003712	molecular_function	transcription coregulator activity
A4	0003713	molecular_function	transcription coactivator activity
A4	0003714	molecular_function	transcription corepressor activity
A4	0003723	molecular_function	RNA binding
A4	0005515	molecular_function	protein binding
A4	0005634	cellular_component	nucleus
A4	0005654	cellular_component	nucleoplasm
A4	0006351	biological_process	DNA-templated transcription
A4	0006397	biological_process	mRNA processing
A4	0008380	biological_process	RNA splicing
A4	0016607	cellular_component	nuclear speck
A4	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
A4	0034244	biological_process	negative regulation of transcription elongation by RNA polymerase II
A4	0042802	molecular_function	identical protein binding
A4	0044390	molecular_function	ubiquitin-like protein conjugating enzyme binding
A4	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A4	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
A4	0070063	molecular_function	RNA polymerase binding
A5	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
A5	0000245	biological_process	spliceosomal complex assembly
A5	0000339	molecular_function	RNA cap binding
A5	0000340	molecular_function	RNA 7-methylguanosine cap binding
A5	0000380	biological_process	alternative mRNA splicing, via spliceosome
A5	0000398	biological_process	mRNA splicing, via spliceosome
A5	0002191	biological_process	cap-dependent translational initiation
A5	0003723	molecular_function	RNA binding
A5	0003729	molecular_function	mRNA binding
A5	0005515	molecular_function	protein binding
A5	0005634	cellular_component	nucleus
A5	0005654	cellular_component	nucleoplasm
A5	0005737	cellular_component	cytoplasm
A5	0005829	cellular_component	cytosol
A5	0005846	cellular_component	nuclear cap binding complex
A5	0006370	biological_process	7-methylguanosine mRNA capping
A5	0006397	biological_process	mRNA processing
A5	0006401	biological_process	RNA catabolic process
A5	0006406	biological_process	mRNA export from nucleus
A5	0006408	biological_process	snRNA export from nucleus
A5	0006417	biological_process	regulation of translation
A5	0006446	biological_process	regulation of translational initiation
A5	0008334	biological_process	histone mRNA metabolic process
A5	0008380	biological_process	RNA splicing
A5	0016070	biological_process	RNA metabolic process
A5	0016071	biological_process	mRNA metabolic process
A5	0030307	biological_process	positive regulation of cell growth
A5	0031047	biological_process	regulatory ncRNA-mediated gene silencing
A5	0031053	biological_process	primary miRNA processing
A5	0031124	biological_process	mRNA 3'-end processing
A5	0031442	biological_process	positive regulation of mRNA 3'-end processing
A5	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
A5	0034518	cellular_component	RNA cap binding complex
A5	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
A5	0035195	biological_process	miRNA-mediated post-transcriptional gene silencing
A5	0042789	biological_process	mRNA transcription by RNA polymerase II
A5	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
A5	0050684	biological_process	regulation of mRNA processing
A5	0051028	biological_process	mRNA transport
A5	0051607	biological_process	defense response to virus
A5	0060090	molecular_function	molecular adaptor activity
A5	1990904	cellular_component	ribonucleoprotein complex
A6	0000380	biological_process	alternative mRNA splicing, via spliceosome
A6	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
A6	0000395	biological_process	mRNA 5'-splice site recognition
A6	0000398	biological_process	mRNA splicing, via spliceosome
A6	0003676	molecular_function	nucleic acid binding
A6	0003723	molecular_function	RNA binding
A6	0003729	molecular_function	mRNA binding
A6	0005515	molecular_function	protein binding
A6	0005634	cellular_component	nucleus
A6	0005654	cellular_component	nucleoplasm
A6	0005681	cellular_component	spliceosomal complex
A6	0005737	cellular_component	cytoplasm
A6	0005829	cellular_component	cytosol
A6	0006376	biological_process	mRNA splice site recognition
A6	0006397	biological_process	mRNA processing
A6	0008380	biological_process	RNA splicing
A6	0016607	cellular_component	nuclear speck
A6	0034504	biological_process	protein localization to nucleus
A6	0035145	cellular_component	exon-exon junction complex
A6	0043484	biological_process	regulation of RNA splicing
A6	0044547	molecular_function	DNA topoisomerase binding
A6	0048255	biological_process	mRNA stabilization
A6	0050733	molecular_function	RS domain binding
A6	0051028	biological_process	mRNA transport
A6	0071013	cellular_component	catalytic step 2 spliceosome
A6	0097398	biological_process	cellular response to interleukin-17
A6	0097400	biological_process	interleukin-17-mediated signaling pathway
A6	0110012	biological_process	protein localization to P-body
B	0000387	biological_process	spliceosomal snRNP assembly
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005684	cellular_component	U2-type spliceosomal complex
B	0005685	cellular_component	U1 snRNP
B	0005686	cellular_component	U2 snRNP
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016607	cellular_component	nuclear speck
B	0030619	molecular_function	U1 snRNA binding
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071007	cellular_component	U2-type catalytic step 2 spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
B	0097525	cellular_component	spliceosomal snRNP complex
B	1903241	biological_process	U2-type prespliceosome assembly
B	1990904	cellular_component	ribonucleoprotein complex
C	0000244	biological_process	spliceosomal tri-snRNP complex assembly
C	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
C	0000387	biological_process	spliceosomal snRNP assembly
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0000932	cellular_component	P-body
C	0000956	biological_process	nuclear-transcribed mRNA catabolic process
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005688	cellular_component	U6 snRNP
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006396	biological_process	RNA processing
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0016020	cellular_component	membrane
C	0017070	molecular_function	U6 snRNA binding
C	0032991	cellular_component	protein-containing complex
C	0033962	biological_process	P-body assembly
C	0042731	molecular_function	PH domain binding
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0097526	cellular_component	spliceosomal tri-snRNP complex
C	0120115	cellular_component	Lsm2-8 complex
C	1990904	cellular_component	ribonucleoprotein complex
D	0000244	biological_process	spliceosomal tri-snRNP complex assembly
D	0000375	biological_process	RNA splicing, via transesterification reactions
D	0000387	biological_process	spliceosomal snRNP assembly
D	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005682	cellular_component	U5 snRNP
D	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
D	0006396	biological_process	RNA processing
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0016607	cellular_component	nuclear speck
D	0071007	cellular_component	U2-type catalytic step 2 spliceosome
D	0071013	cellular_component	catalytic step 2 spliceosome
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000387	biological_process	spliceosomal snRNP assembly
E	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003676	molecular_function	nucleic acid binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005684	cellular_component	U2-type spliceosomal complex
E	0005686	cellular_component	U2 snRNP
E	0005689	cellular_component	U12-type spliceosomal complex
E	0005730	cellular_component	nucleolus
E	0006282	biological_process	regulation of DNA repair
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0030620	molecular_function	U2 snRNA binding
E	0042177	biological_process	negative regulation of protein catabolic process
E	0043484	biological_process	regulation of RNA splicing
E	0044877	molecular_function	protein-containing complex binding
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0071005	cellular_component	U2-type precatalytic spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
E	1903241	biological_process	U2-type prespliceosome assembly
F	0000245	biological_process	spliceosomal complex assembly
F	0000387	biological_process	spliceosomal snRNP assembly
F	0000389	biological_process	mRNA 3'-splice site recognition
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0005684	cellular_component	U2-type spliceosomal complex
F	0005686	cellular_component	U2 snRNP
F	0006397	biological_process	mRNA processing
F	0008270	molecular_function	zinc ion binding
F	0008380	biological_process	RNA splicing
F	0010976	biological_process	positive regulation of neuron projection development
F	0016607	cellular_component	nuclear speck
F	0046872	molecular_function	metal ion binding
F	0071004	cellular_component	U2-type prespliceosome
F	0071005	cellular_component	U2-type precatalytic spliceosome
F	0071013	cellular_component	catalytic step 2 spliceosome
F	1903241	biological_process	U2-type prespliceosome assembly
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0000974	cellular_component	Prp19 complex
G	0001650	cellular_component	fibrillar center
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005662	cellular_component	DNA replication factor A complex
G	0005681	cellular_component	spliceosomal complex
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
G	0016607	cellular_component	nuclear speck
G	0031965	cellular_component	nuclear membrane
G	0071007	cellular_component	U2-type catalytic step 2 spliceosome
G	0071013	cellular_component	catalytic step 2 spliceosome
H	0000244	biological_process	spliceosomal tri-snRNP complex assembly
H	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
H	0000387	biological_process	spliceosomal snRNP assembly
H	0000398	biological_process	mRNA splicing, via spliceosome
H	0003723	molecular_function	RNA binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005681	cellular_component	spliceosomal complex
H	0005688	cellular_component	U6 snRNP
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006397	biological_process	mRNA processing
H	0006402	biological_process	mRNA catabolic process
H	0008380	biological_process	RNA splicing
H	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
H	0046982	molecular_function	protein heterodimerization activity
H	0071005	cellular_component	U2-type precatalytic spliceosome
H	0120115	cellular_component	Lsm2-8 complex
H	1990726	cellular_component	Lsm1-7-Pat1 complex
H	1990904	cellular_component	ribonucleoprotein complex
I	0000398	biological_process	mRNA splicing, via spliceosome
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005681	cellular_component	spliceosomal complex
I	0006397	biological_process	mRNA processing
I	0008380	biological_process	RNA splicing
I	0071005	cellular_component	U2-type precatalytic spliceosome
I	0071011	cellular_component	precatalytic spliceosome
J	0000244	biological_process	spliceosomal tri-snRNP complex assembly
J	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
J	0000387	biological_process	spliceosomal snRNP assembly
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0000932	cellular_component	P-body
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005681	cellular_component	spliceosomal complex
J	0005688	cellular_component	U6 snRNP
J	0005730	cellular_component	nucleolus
J	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006364	biological_process	rRNA processing
J	0006397	biological_process	mRNA processing
J	0006402	biological_process	mRNA catabolic process
J	0008033	biological_process	tRNA processing
J	0008380	biological_process	RNA splicing
J	0030490	biological_process	maturation of SSU-rRNA
J	0030532	cellular_component	small nuclear ribonucleoprotein complex
J	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
J	0046982	molecular_function	protein heterodimerization activity
J	0071005	cellular_component	U2-type precatalytic spliceosome
J	0120115	cellular_component	Lsm2-8 complex
J	1990904	cellular_component	ribonucleoprotein complex
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0001527	cellular_component	microfibril
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005681	cellular_component	spliceosomal complex
K	0005684	cellular_component	U2-type spliceosomal complex
K	0006397	biological_process	mRNA processing
K	0008380	biological_process	RNA splicing
K	0071005	cellular_component	U2-type precatalytic spliceosome
L	0000077	biological_process	DNA damage checkpoint signaling
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0000974	cellular_component	Prp19 complex
L	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
L	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
L	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
L	0003677	molecular_function	DNA binding
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005662	cellular_component	DNA replication factor A complex
L	0005681	cellular_component	spliceosomal complex
L	0005737	cellular_component	cytoplasm
L	0006281	biological_process	DNA repair
L	0006351	biological_process	DNA-templated transcription
L	0006355	biological_process	regulation of DNA-templated transcription
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0006397	biological_process	mRNA processing
L	0006974	biological_process	DNA damage response
L	0008380	biological_process	RNA splicing
L	0016020	cellular_component	membrane
L	0016607	cellular_component	nuclear speck
L	0019904	molecular_function	protein domain specific binding
L	0042802	molecular_function	identical protein binding
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0071007	cellular_component	U2-type catalytic step 2 spliceosome
L	0071013	cellular_component	catalytic step 2 spliceosome
L	0071987	molecular_function	WD40-repeat domain binding
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0003676	molecular_function	nucleic acid binding
N	0003677	molecular_function	DNA binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005681	cellular_component	spliceosomal complex
N	0006397	biological_process	mRNA processing
N	0008270	molecular_function	zinc ion binding
N	0008380	biological_process	RNA splicing
N	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
N	0046872	molecular_function	metal ion binding
N	0071005	cellular_component	U2-type precatalytic spliceosome
P	0000398	biological_process	mRNA splicing, via spliceosome
P	0000974	cellular_component	Prp19 complex
P	0003676	molecular_function	nucleic acid binding
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005681	cellular_component	spliceosomal complex
P	0005737	cellular_component	cytoplasm
P	0006397	biological_process	mRNA processing
P	0008270	molecular_function	zinc ion binding
P	0008380	biological_process	RNA splicing
P	0017070	molecular_function	U6 snRNA binding
P	0033120	biological_process	positive regulation of RNA splicing
P	0036002	molecular_function	pre-mRNA binding
P	0042307	biological_process	positive regulation of protein import into nucleus
P	0045292	biological_process	mRNA cis splicing, via spliceosome
P	0046827	biological_process	positive regulation of protein export from nucleus
P	0046872	molecular_function	metal ion binding
P	0048306	molecular_function	calcium-dependent protein binding
P	0071006	cellular_component	U2-type catalytic step 1 spliceosome
P	0071007	cellular_component	U2-type catalytic step 2 spliceosome
P	0071013	cellular_component	catalytic step 2 spliceosome
P	0071466	biological_process	cellular response to xenobiotic stimulus
Q	0000398	biological_process	mRNA splicing, via spliceosome
Q	0000785	cellular_component	chromatin
Q	0003713	molecular_function	transcription coactivator activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005681	cellular_component	spliceosomal complex
Q	0006351	biological_process	DNA-templated transcription
Q	0006397	biological_process	mRNA processing
Q	0008380	biological_process	RNA splicing
Q	0016922	molecular_function	nuclear receptor binding
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0003723	molecular_function	RNA binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005681	cellular_component	spliceosomal complex
R	0006397	biological_process	mRNA processing
R	0008380	biological_process	RNA splicing
R	0016607	cellular_component	nuclear speck
R	0045292	biological_process	mRNA cis splicing, via spliceosome
R	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0071013	cellular_component	catalytic step 2 spliceosome
T	0000387	biological_process	spliceosomal snRNP assembly
T	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0003723	molecular_function	RNA binding
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005681	cellular_component	spliceosomal complex
T	0005684	cellular_component	U2-type spliceosomal complex
T	0005686	cellular_component	U2 snRNP
T	0005689	cellular_component	U12-type spliceosomal complex
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0016607	cellular_component	nuclear speck
T	0071005	cellular_component	U2-type precatalytic spliceosome
T	0071011	cellular_component	precatalytic spliceosome
T	0071013	cellular_component	catalytic step 2 spliceosome
T	1903241	biological_process	U2-type prespliceosome assembly
V	0000244	biological_process	spliceosomal tri-snRNP complex assembly
V	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
V	0000387	biological_process	spliceosomal snRNP assembly
V	0000398	biological_process	mRNA splicing, via spliceosome
V	0000932	cellular_component	P-body
V	0003723	molecular_function	RNA binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005681	cellular_component	spliceosomal complex
V	0005688	cellular_component	U6 snRNP
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006397	biological_process	mRNA processing
V	0006402	biological_process	mRNA catabolic process
V	0008380	biological_process	RNA splicing
V	0017070	molecular_function	U6 snRNA binding
V	0031267	molecular_function	small GTPase binding
V	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
V	0071005	cellular_component	U2-type precatalytic spliceosome
V	0071011	cellular_component	precatalytic spliceosome
V	0071013	cellular_component	catalytic step 2 spliceosome
V	0120115	cellular_component	Lsm2-8 complex
V	1990726	cellular_component	Lsm1-7-Pat1 complex
V	1990904	cellular_component	ribonucleoprotein complex
W	0000387	biological_process	spliceosomal snRNP assembly
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0003723	molecular_function	RNA binding
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005681	cellular_component	spliceosomal complex
W	0005684	cellular_component	U2-type spliceosomal complex
W	0005686	cellular_component	U2 snRNP
W	0006397	biological_process	mRNA processing
W	0007283	biological_process	spermatogenesis
W	0008380	biological_process	RNA splicing
W	0016604	cellular_component	nuclear body
W	0016607	cellular_component	nuclear speck
W	0030532	cellular_component	small nuclear ribonucleoprotein complex
W	0030620	molecular_function	U2 snRNA binding
W	0071005	cellular_component	U2-type precatalytic spliceosome
W	0071007	cellular_component	U2-type catalytic step 2 spliceosome
W	0071013	cellular_component	catalytic step 2 spliceosome
W	1903241	biological_process	U2-type prespliceosome assembly
W	1990904	cellular_component	ribonucleoprotein complex
X	0003697	molecular_function	single-stranded DNA binding
X	0003723	molecular_function	RNA binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006364	biological_process	rRNA processing
X	0006396	biological_process	RNA processing
X	0006397	biological_process	mRNA processing
X	0008380	biological_process	RNA splicing
X	0019888	molecular_function	protein phosphatase regulator activity
X	0050699	molecular_function	WW domain binding
Y	0000375	biological_process	RNA splicing, via transesterification reactions
Y	0000398	biological_process	mRNA splicing, via spliceosome
Y	0003677	molecular_function	DNA binding
Y	0003723	molecular_function	RNA binding
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005681	cellular_component	spliceosomal complex
Y	0005829	cellular_component	cytosol
Y	0006397	biological_process	mRNA processing
Y	0008380	biological_process	RNA splicing
Y	0016363	cellular_component	nuclear matrix
Y	0016607	cellular_component	nuclear speck
Y	0048024	biological_process	regulation of mRNA splicing, via spliceosome
Y	0071013	cellular_component	catalytic step 2 spliceosome
a	0000244	biological_process	spliceosomal tri-snRNP complex assembly
a	0000245	biological_process	spliceosomal complex assembly
a	0000387	biological_process	spliceosomal snRNP assembly
a	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005682	cellular_component	U5 snRNP
a	0005684	cellular_component	U2-type spliceosomal complex
a	0005685	cellular_component	U1 snRNP
a	0005686	cellular_component	U2 snRNP
a	0005687	cellular_component	U4 snRNP
a	0005689	cellular_component	U12-type spliceosomal complex
a	0005829	cellular_component	cytosol
a	0006397	biological_process	mRNA processing
a	0008380	biological_process	RNA splicing
a	0030532	cellular_component	small nuclear ribonucleoprotein complex
a	0034709	cellular_component	methylosome
a	0034715	cellular_component	pICln-Sm protein complex
a	0034719	cellular_component	SMN-Sm protein complex
a	0036261	biological_process	7-methylguanosine cap hypermethylation
a	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
a	0070062	cellular_component	extracellular exosome
a	0071005	cellular_component	U2-type precatalytic spliceosome
a	0071007	cellular_component	U2-type catalytic step 2 spliceosome
a	0071011	cellular_component	precatalytic spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0097525	cellular_component	spliceosomal snRNP complex
a	1903241	biological_process	U2-type prespliceosome assembly
a	1990904	cellular_component	ribonucleoprotein complex
b	0000244	biological_process	spliceosomal tri-snRNP complex assembly
b	0000245	biological_process	spliceosomal complex assembly
b	0000387	biological_process	spliceosomal snRNP assembly
b	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005683	cellular_component	U7 snRNP
b	0005684	cellular_component	U2-type spliceosomal complex
b	0005685	cellular_component	U1 snRNP
b	0005687	cellular_component	U4 snRNP
b	0005689	cellular_component	U12-type spliceosomal complex
b	0005829	cellular_component	cytosol
b	0006397	biological_process	mRNA processing
b	0008380	biological_process	RNA splicing
b	0022618	biological_process	protein-RNA complex assembly
b	0030532	cellular_component	small nuclear ribonucleoprotein complex
b	0034709	cellular_component	methylosome
b	0034715	cellular_component	pICln-Sm protein complex
b	0034719	cellular_component	SMN-Sm protein complex
b	0036261	biological_process	7-methylguanosine cap hypermethylation
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
b	0071005	cellular_component	U2-type precatalytic spliceosome
b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	0071045	biological_process	nuclear histone mRNA catabolic process
b	1903241	biological_process	U2-type prespliceosome assembly
b	1990904	cellular_component	ribonucleoprotein complex
c	0000244	biological_process	spliceosomal tri-snRNP complex assembly
c	0000245	biological_process	spliceosomal complex assembly
c	0000387	biological_process	spliceosomal snRNP assembly
c	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
c	0000398	biological_process	mRNA splicing, via spliceosome
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005681	cellular_component	spliceosomal complex
c	0005682	cellular_component	U5 snRNP
c	0005683	cellular_component	U7 snRNP
c	0005684	cellular_component	U2-type spliceosomal complex
c	0005685	cellular_component	U1 snRNP
c	0005686	cellular_component	U2 snRNP
c	0005687	cellular_component	U4 snRNP
c	0005689	cellular_component	U12-type spliceosomal complex
c	0005697	cellular_component	telomerase holoenzyme complex
c	0005829	cellular_component	cytosol
c	0006397	biological_process	mRNA processing
c	0008380	biological_process	RNA splicing
c	0030532	cellular_component	small nuclear ribonucleoprotein complex
c	0034709	cellular_component	methylosome
c	0034715	cellular_component	pICln-Sm protein complex
c	0034719	cellular_component	SMN-Sm protein complex
c	0036261	biological_process	7-methylguanosine cap hypermethylation
c	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
c	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
c	0071005	cellular_component	U2-type precatalytic spliceosome
c	0071007	cellular_component	U2-type catalytic step 2 spliceosome
c	0071011	cellular_component	precatalytic spliceosome
c	0071013	cellular_component	catalytic step 2 spliceosome
c	0071045	biological_process	nuclear histone mRNA catabolic process
c	1903241	biological_process	U2-type prespliceosome assembly
c	1990904	cellular_component	ribonucleoprotein complex
d	0000244	biological_process	spliceosomal tri-snRNP complex assembly
d	0000245	biological_process	spliceosomal complex assembly
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005683	cellular_component	U7 snRNP
d	0005684	cellular_component	U2-type spliceosomal complex
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005689	cellular_component	U12-type spliceosomal complex
d	0005829	cellular_component	cytosol
d	0006397	biological_process	mRNA processing
d	0008380	biological_process	RNA splicing
d	0030532	cellular_component	small nuclear ribonucleoprotein complex
d	0034709	cellular_component	methylosome
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0043186	cellular_component	P granule
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
d	0071004	cellular_component	U2-type prespliceosome
d	0071005	cellular_component	U2-type precatalytic spliceosome
d	0071007	cellular_component	U2-type catalytic step 2 spliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	0071045	biological_process	nuclear histone mRNA catabolic process
d	0097526	cellular_component	spliceosomal tri-snRNP complex
d	1903241	biological_process	U2-type prespliceosome assembly
d	1990904	cellular_component	ribonucleoprotein complex
e	0000243	cellular_component	commitment complex
e	0000244	biological_process	spliceosomal tri-snRNP complex assembly
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005683	cellular_component	U7 snRNP
e	0005684	cellular_component	U2-type spliceosomal complex
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005689	cellular_component	U12-type spliceosomal complex
e	0005697	cellular_component	telomerase holoenzyme complex
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0006396	biological_process	RNA processing
e	0006397	biological_process	mRNA processing
e	0006479	biological_process	protein methylation
e	0008380	biological_process	RNA splicing
e	0016604	cellular_component	nuclear body
e	0019899	molecular_function	enzyme binding
e	0030532	cellular_component	small nuclear ribonucleoprotein complex
e	0034709	cellular_component	methylosome
e	0034715	cellular_component	pICln-Sm protein complex
e	0034719	cellular_component	SMN-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
e	0070034	molecular_function	telomerase RNA binding
e	0071005	cellular_component	U2-type precatalytic spliceosome
e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	0071045	biological_process	nuclear histone mRNA catabolic process
e	0071208	molecular_function	histone pre-mRNA DCP binding
e	0071209	molecular_function	U7 snRNA binding
e	0097526	cellular_component	spliceosomal tri-snRNP complex
e	1903241	biological_process	U2-type prespliceosome assembly
e	1990904	cellular_component	ribonucleoprotein complex
f	0000244	biological_process	spliceosomal tri-snRNP complex assembly
f	0000245	biological_process	spliceosomal complex assembly
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005683	cellular_component	U7 snRNP
f	0005684	cellular_component	U2-type spliceosomal complex
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005689	cellular_component	U12-type spliceosomal complex
f	0005697	cellular_component	telomerase holoenzyme complex
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0006397	biological_process	mRNA processing
f	0006479	biological_process	protein methylation
f	0008380	biological_process	RNA splicing
f	0030532	cellular_component	small nuclear ribonucleoprotein complex
f	0034709	cellular_component	methylosome
f	0034719	cellular_component	SMN-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
f	0070034	molecular_function	telomerase RNA binding
f	0070990	molecular_function	snRNP binding
f	0071004	cellular_component	U2-type prespliceosome
f	0071005	cellular_component	U2-type precatalytic spliceosome
f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0071045	biological_process	nuclear histone mRNA catabolic process
f	0071204	cellular_component	histone pre-mRNA 3'end processing complex
f	0071208	molecular_function	histone pre-mRNA DCP binding
f	1903241	biological_process	U2-type prespliceosome assembly
f	1990446	molecular_function	U1 snRNP binding
f	1990447	molecular_function	U2 snRNP binding
f	1990904	cellular_component	ribonucleoprotein complex
g	0000243	cellular_component	commitment complex
g	0000244	biological_process	spliceosomal tri-snRNP complex assembly
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005684	cellular_component	U2-type spliceosomal complex
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005689	cellular_component	U12-type spliceosomal complex
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006396	biological_process	RNA processing
g	0006397	biological_process	mRNA processing
g	0008380	biological_process	RNA splicing
g	0030532	cellular_component	small nuclear ribonucleoprotein complex
g	0034709	cellular_component	methylosome
g	0034715	cellular_component	pICln-Sm protein complex
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
g	0071005	cellular_component	U2-type precatalytic spliceosome
g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
g	1990446	molecular_function	U1 snRNP binding
g	1990904	cellular_component	ribonucleoprotein complex
h	0000244	biological_process	spliceosomal tri-snRNP complex assembly
h	0000245	biological_process	spliceosomal complex assembly
h	0000387	biological_process	spliceosomal snRNP assembly
h	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0003723	molecular_function	RNA binding
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005681	cellular_component	spliceosomal complex
h	0005682	cellular_component	U5 snRNP
h	0005684	cellular_component	U2-type spliceosomal complex
h	0005685	cellular_component	U1 snRNP
h	0005686	cellular_component	U2 snRNP
h	0005687	cellular_component	U4 snRNP
h	0005689	cellular_component	U12-type spliceosomal complex
h	0005829	cellular_component	cytosol
h	0006397	biological_process	mRNA processing
h	0008380	biological_process	RNA splicing
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0034709	cellular_component	methylosome
h	0034715	cellular_component	pICln-Sm protein complex
h	0034719	cellular_component	SMN-Sm protein complex
h	0036261	biological_process	7-methylguanosine cap hypermethylation
h	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
h	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
h	0070062	cellular_component	extracellular exosome
h	0071005	cellular_component	U2-type precatalytic spliceosome
h	0071007	cellular_component	U2-type catalytic step 2 spliceosome
h	0071011	cellular_component	precatalytic spliceosome
h	0071013	cellular_component	catalytic step 2 spliceosome
h	0097525	cellular_component	spliceosomal snRNP complex
h	1903241	biological_process	U2-type prespliceosome assembly
h	1990904	cellular_component	ribonucleoprotein complex
i	0000244	biological_process	spliceosomal tri-snRNP complex assembly
i	0000245	biological_process	spliceosomal complex assembly
i	0000387	biological_process	spliceosomal snRNP assembly
i	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
i	0000398	biological_process	mRNA splicing, via spliceosome
i	0003723	molecular_function	RNA binding
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005681	cellular_component	spliceosomal complex
i	0005683	cellular_component	U7 snRNP
i	0005684	cellular_component	U2-type spliceosomal complex
i	0005685	cellular_component	U1 snRNP
i	0005687	cellular_component	U4 snRNP
i	0005689	cellular_component	U12-type spliceosomal complex
i	0005829	cellular_component	cytosol
i	0006397	biological_process	mRNA processing
i	0008380	biological_process	RNA splicing
i	0022618	biological_process	protein-RNA complex assembly
i	0030532	cellular_component	small nuclear ribonucleoprotein complex
i	0034709	cellular_component	methylosome
i	0034715	cellular_component	pICln-Sm protein complex
i	0034719	cellular_component	SMN-Sm protein complex
i	0036261	biological_process	7-methylguanosine cap hypermethylation
i	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
i	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
i	0071005	cellular_component	U2-type precatalytic spliceosome
i	0071007	cellular_component	U2-type catalytic step 2 spliceosome
i	0071013	cellular_component	catalytic step 2 spliceosome
i	0071045	biological_process	nuclear histone mRNA catabolic process
i	1903241	biological_process	U2-type prespliceosome assembly
i	1990904	cellular_component	ribonucleoprotein complex
j	0000244	biological_process	spliceosomal tri-snRNP complex assembly
j	0000245	biological_process	spliceosomal complex assembly
j	0000387	biological_process	spliceosomal snRNP assembly
j	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
j	0000398	biological_process	mRNA splicing, via spliceosome
j	0003723	molecular_function	RNA binding
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005681	cellular_component	spliceosomal complex
j	0005682	cellular_component	U5 snRNP
j	0005683	cellular_component	U7 snRNP
j	0005684	cellular_component	U2-type spliceosomal complex
j	0005685	cellular_component	U1 snRNP
j	0005686	cellular_component	U2 snRNP
j	0005687	cellular_component	U4 snRNP
j	0005689	cellular_component	U12-type spliceosomal complex
j	0005697	cellular_component	telomerase holoenzyme complex
j	0005829	cellular_component	cytosol
j	0006397	biological_process	mRNA processing
j	0008380	biological_process	RNA splicing
j	0030532	cellular_component	small nuclear ribonucleoprotein complex
j	0034709	cellular_component	methylosome
j	0034715	cellular_component	pICln-Sm protein complex
j	0034719	cellular_component	SMN-Sm protein complex
j	0036261	biological_process	7-methylguanosine cap hypermethylation
j	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
j	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
j	0071005	cellular_component	U2-type precatalytic spliceosome
j	0071007	cellular_component	U2-type catalytic step 2 spliceosome
j	0071011	cellular_component	precatalytic spliceosome
j	0071013	cellular_component	catalytic step 2 spliceosome
j	0071045	biological_process	nuclear histone mRNA catabolic process
j	1903241	biological_process	U2-type prespliceosome assembly
j	1990904	cellular_component	ribonucleoprotein complex
k	0000244	biological_process	spliceosomal tri-snRNP complex assembly
k	0000245	biological_process	spliceosomal complex assembly
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005683	cellular_component	U7 snRNP
k	0005684	cellular_component	U2-type spliceosomal complex
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005689	cellular_component	U12-type spliceosomal complex
k	0005829	cellular_component	cytosol
k	0006397	biological_process	mRNA processing
k	0008380	biological_process	RNA splicing
k	0030532	cellular_component	small nuclear ribonucleoprotein complex
k	0034709	cellular_component	methylosome
k	0034719	cellular_component	SMN-Sm protein complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0043186	cellular_component	P granule
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
k	0071004	cellular_component	U2-type prespliceosome
k	0071005	cellular_component	U2-type precatalytic spliceosome
k	0071007	cellular_component	U2-type catalytic step 2 spliceosome
k	0071011	cellular_component	precatalytic spliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	0071045	biological_process	nuclear histone mRNA catabolic process
k	0097526	cellular_component	spliceosomal tri-snRNP complex
k	1903241	biological_process	U2-type prespliceosome assembly
k	1990904	cellular_component	ribonucleoprotein complex
l	0000243	cellular_component	commitment complex
l	0000244	biological_process	spliceosomal tri-snRNP complex assembly
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005683	cellular_component	U7 snRNP
l	0005684	cellular_component	U2-type spliceosomal complex
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005689	cellular_component	U12-type spliceosomal complex
l	0005697	cellular_component	telomerase holoenzyme complex
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006396	biological_process	RNA processing
l	0006397	biological_process	mRNA processing
l	0006479	biological_process	protein methylation
l	0008380	biological_process	RNA splicing
l	0016604	cellular_component	nuclear body
l	0019899	molecular_function	enzyme binding
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034709	cellular_component	methylosome
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
l	0070034	molecular_function	telomerase RNA binding
l	0071005	cellular_component	U2-type precatalytic spliceosome
l	0071007	cellular_component	U2-type catalytic step 2 spliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	0071045	biological_process	nuclear histone mRNA catabolic process
l	0071208	molecular_function	histone pre-mRNA DCP binding
l	0071209	molecular_function	U7 snRNA binding
l	0097526	cellular_component	spliceosomal tri-snRNP complex
l	1903241	biological_process	U2-type prespliceosome assembly
l	1990904	cellular_component	ribonucleoprotein complex
m	0000244	biological_process	spliceosomal tri-snRNP complex assembly
m	0000245	biological_process	spliceosomal complex assembly
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005683	cellular_component	U7 snRNP
m	0005684	cellular_component	U2-type spliceosomal complex
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005689	cellular_component	U12-type spliceosomal complex
m	0005697	cellular_component	telomerase holoenzyme complex
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0006479	biological_process	protein methylation
m	0008380	biological_process	RNA splicing
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0034709	cellular_component	methylosome
m	0034719	cellular_component	SMN-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
m	0070034	molecular_function	telomerase RNA binding
m	0070990	molecular_function	snRNP binding
m	0071004	cellular_component	U2-type prespliceosome
m	0071005	cellular_component	U2-type precatalytic spliceosome
m	0071007	cellular_component	U2-type catalytic step 2 spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	0071045	biological_process	nuclear histone mRNA catabolic process
m	0071204	cellular_component	histone pre-mRNA 3'end processing complex
m	0071208	molecular_function	histone pre-mRNA DCP binding
m	1903241	biological_process	U2-type prespliceosome assembly
m	1990446	molecular_function	U1 snRNP binding
m	1990447	molecular_function	U2 snRNP binding
m	1990904	cellular_component	ribonucleoprotein complex
n	0000243	cellular_component	commitment complex
n	0000244	biological_process	spliceosomal tri-snRNP complex assembly
n	0000245	biological_process	spliceosomal complex assembly
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005684	cellular_component	U2-type spliceosomal complex
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005689	cellular_component	U12-type spliceosomal complex
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006396	biological_process	RNA processing
n	0006397	biological_process	mRNA processing
n	0008380	biological_process	RNA splicing
n	0030532	cellular_component	small nuclear ribonucleoprotein complex
n	0034709	cellular_component	methylosome
n	0034715	cellular_component	pICln-Sm protein complex
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
n	0071005	cellular_component	U2-type precatalytic spliceosome
n	0071007	cellular_component	U2-type catalytic step 2 spliceosome
n	0071011	cellular_component	precatalytic spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0097526	cellular_component	spliceosomal tri-snRNP complex
n	1903241	biological_process	U2-type prespliceosome assembly
n	1990446	molecular_function	U1 snRNP binding
n	1990904	cellular_component	ribonucleoprotein complex
p	0000387	biological_process	spliceosomal snRNP assembly
p	0000389	biological_process	mRNA 3'-splice site recognition
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0003723	molecular_function	RNA binding
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0005681	cellular_component	spliceosomal complex
p	0005684	cellular_component	U2-type spliceosomal complex
p	0005686	cellular_component	U2 snRNP
p	0006396	biological_process	RNA processing
p	0006397	biological_process	mRNA processing
p	0008380	biological_process	RNA splicing
p	0016607	cellular_component	nuclear speck
p	0045292	biological_process	mRNA cis splicing, via spliceosome
p	0071004	cellular_component	U2-type prespliceosome
p	0071005	cellular_component	U2-type precatalytic spliceosome
p	0071013	cellular_component	catalytic step 2 spliceosome
p	1903241	biological_process	U2-type prespliceosome assembly
q	0000398	biological_process	mRNA splicing, via spliceosome
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005737	cellular_component	cytoplasm
q	0015030	cellular_component	Cajal body
q	0031386	molecular_function	protein tag activity
q	0036211	biological_process	protein modification process
q	1903955	biological_process	positive regulation of protein targeting to mitochondrion
r	0000166	molecular_function	nucleotide binding
r	0000244	biological_process	spliceosomal tri-snRNP complex assembly
r	0000387	biological_process	spliceosomal snRNP assembly
r	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0003723	molecular_function	RNA binding
r	0003924	molecular_function	GTPase activity
r	0005515	molecular_function	protein binding
r	0005525	molecular_function	GTP binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005681	cellular_component	spliceosomal complex
r	0005829	cellular_component	cytosol
r	0006397	biological_process	mRNA processing
r	0008380	biological_process	RNA splicing
r	0015030	cellular_component	Cajal body
r	0016020	cellular_component	membrane
r	0016607	cellular_component	nuclear speck
r	0030623	molecular_function	U5 snRNA binding
r	0042220	biological_process	response to cocaine
r	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
r	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
r	0071005	cellular_component	U2-type precatalytic spliceosome
r	0071007	cellular_component	U2-type catalytic step 2 spliceosome
r	0071013	cellular_component	catalytic step 2 spliceosome
r	0071466	biological_process	cellular response to xenobiotic stimulus
s	0000166	molecular_function	nucleotide binding
s	0000244	biological_process	spliceosomal tri-snRNP complex assembly
s	0000354	biological_process	cis assembly of pre-catalytic spliceosome
s	0000387	biological_process	spliceosomal snRNP assembly
s	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
s	0000398	biological_process	mRNA splicing, via spliceosome
s	0001649	biological_process	osteoblast differentiation
s	0003676	molecular_function	nucleic acid binding
s	0003723	molecular_function	RNA binding
s	0003724	molecular_function	RNA helicase activity
s	0004386	molecular_function	helicase activity
s	0005515	molecular_function	protein binding
s	0005524	molecular_function	ATP binding
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0005681	cellular_component	spliceosomal complex
s	0005682	cellular_component	U5 snRNP
s	0006397	biological_process	mRNA processing
s	0008380	biological_process	RNA splicing
s	0016020	cellular_component	membrane
s	0016787	molecular_function	hydrolase activity
s	0016887	molecular_function	ATP hydrolysis activity
s	0030532	cellular_component	small nuclear ribonucleoprotein complex
s	0042802	molecular_function	identical protein binding
s	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
s	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
s	0071005	cellular_component	U2-type precatalytic spliceosome
s	0071006	cellular_component	U2-type catalytic step 1 spliceosome
s	0071013	cellular_component	catalytic step 2 spliceosome
u	0000245	biological_process	spliceosomal complex assembly
u	0000375	biological_process	RNA splicing, via transesterification reactions
u	0000387	biological_process	spliceosomal snRNP assembly
u	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
u	0000398	biological_process	mRNA splicing, via spliceosome
u	0000785	cellular_component	chromatin
u	0003723	molecular_function	RNA binding
u	0003729	molecular_function	mRNA binding
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005681	cellular_component	spliceosomal complex
u	0005684	cellular_component	U2-type spliceosomal complex
u	0005686	cellular_component	U2 snRNP
u	0005689	cellular_component	U12-type spliceosomal complex
u	0005730	cellular_component	nucleolus
u	0006338	biological_process	chromatin remodeling
u	0006397	biological_process	mRNA processing
u	0008380	biological_process	RNA splicing
u	0016607	cellular_component	nuclear speck
u	0031981	cellular_component	nuclear lumen
u	0034693	cellular_component	U11/U12 snRNP
u	0036002	molecular_function	pre-mRNA binding
u	0045943	biological_process	positive regulation of transcription by RNA polymerase I
u	0045944	biological_process	positive regulation of transcription by RNA polymerase II
u	0045945	biological_process	positive regulation of transcription by RNA polymerase III
u	0071004	cellular_component	U2-type prespliceosome
u	0071005	cellular_component	U2-type precatalytic spliceosome
u	0071013	cellular_component	catalytic step 2 spliceosome
u	1903241	biological_process	U2-type prespliceosome assembly
u	1990935	molecular_function	splicing factor binding
v	0000122	biological_process	negative regulation of transcription by RNA polymerase II
v	0000398	biological_process	mRNA splicing, via spliceosome
v	0003713	molecular_function	transcription coactivator activity
v	0003714	molecular_function	transcription corepressor activity
v	0003723	molecular_function	RNA binding
v	0005112	molecular_function	Notch binding
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005681	cellular_component	spliceosomal complex
v	0006351	biological_process	DNA-templated transcription
v	0006357	biological_process	regulation of transcription by RNA polymerase II
v	0006397	biological_process	mRNA processing
v	0008024	cellular_component	cyclin/CDK positive transcription elongation factor complex
v	0008380	biological_process	RNA splicing
v	0016363	cellular_component	nuclear matrix
v	0016607	cellular_component	nuclear speck
v	0016922	molecular_function	nuclear receptor binding
v	0019899	molecular_function	enzyme binding
v	0030511	biological_process	positive regulation of transforming growth factor beta receptor signaling pathway
v	0042771	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
v	0042809	molecular_function	nuclear vitamin D receptor binding
v	0042974	molecular_function	nuclear retinoic acid receptor binding
v	0043923	biological_process	host-mediated activation of viral transcription
v	0045892	biological_process	negative regulation of DNA-templated transcription
v	0045944	biological_process	positive regulation of transcription by RNA polymerase II
v	0046332	molecular_function	SMAD binding
v	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
v	0048255	biological_process	mRNA stabilization
v	0048384	biological_process	retinoic acid receptor signaling pathway
v	0048385	biological_process	regulation of retinoic acid receptor signaling pathway
v	0050681	molecular_function	nuclear androgen receptor binding
v	0050769	biological_process	positive regulation of neurogenesis
v	0070562	biological_process	regulation of vitamin D receptor signaling pathway
v	0070564	biological_process	positive regulation of vitamin D receptor signaling pathway
v	0071007	cellular_component	U2-type catalytic step 2 spliceosome
v	0071013	cellular_component	catalytic step 2 spliceosome
v	0071300	biological_process	cellular response to retinoic acid
w	0000375	biological_process	RNA splicing, via transesterification reactions
w	0000387	biological_process	spliceosomal snRNP assembly
w	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
w	0000398	biological_process	mRNA splicing, via spliceosome
w	0003676	molecular_function	nucleic acid binding
w	0003723	molecular_function	RNA binding
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005654	cellular_component	nucleoplasm
w	0005681	cellular_component	spliceosomal complex
w	0005684	cellular_component	U2-type spliceosomal complex
w	0005686	cellular_component	U2 snRNP
w	0005689	cellular_component	U12-type spliceosomal complex
w	0006397	biological_process	mRNA processing
w	0008380	biological_process	RNA splicing
w	0071005	cellular_component	U2-type precatalytic spliceosome
w	0071011	cellular_component	precatalytic spliceosome
w	1903241	biological_process	U2-type prespliceosome assembly
w	1990935	molecular_function	splicing factor binding
x	0000387	biological_process	spliceosomal snRNP assembly
x	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
x	0000398	biological_process	mRNA splicing, via spliceosome
x	0003723	molecular_function	RNA binding
x	0005515	molecular_function	protein binding
x	0005634	cellular_component	nucleus
x	0005654	cellular_component	nucleoplasm
x	0005681	cellular_component	spliceosomal complex
x	0005684	cellular_component	U2-type spliceosomal complex
x	0005686	cellular_component	U2 snRNP
x	0005689	cellular_component	U12-type spliceosomal complex
x	0006282	biological_process	regulation of DNA repair
x	0006397	biological_process	mRNA processing
x	0008380	biological_process	RNA splicing
x	0043484	biological_process	regulation of RNA splicing
x	0045893	biological_process	positive regulation of DNA-templated transcription
x	0071005	cellular_component	U2-type precatalytic spliceosome
x	0071011	cellular_component	precatalytic spliceosome
x	1903241	biological_process	U2-type prespliceosome assembly
x	1990935	molecular_function	splicing factor binding
y	0000387	biological_process	spliceosomal snRNP assembly
y	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0003677	molecular_function	DNA binding
y	0003723	molecular_function	RNA binding
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005681	cellular_component	spliceosomal complex
y	0005684	cellular_component	U2-type spliceosomal complex
y	0005686	cellular_component	U2 snRNP
y	0005689	cellular_component	U12-type spliceosomal complex
y	0006351	biological_process	DNA-templated transcription
y	0006397	biological_process	mRNA processing
y	0008270	molecular_function	zinc ion binding
y	0008380	biological_process	RNA splicing
y	0016363	cellular_component	nuclear matrix
y	0016607	cellular_component	nuclear speck
y	0045893	biological_process	positive regulation of DNA-templated transcription
y	0046872	molecular_function	metal ion binding
y	0048863	biological_process	stem cell differentiation
y	0071005	cellular_component	U2-type precatalytic spliceosome
y	0071011	cellular_component	precatalytic spliceosome
y	1903241	biological_process	U2-type prespliceosome assembly
z	0000387	biological_process	spliceosomal snRNP assembly
z	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
z	0000398	biological_process	mRNA splicing, via spliceosome
z	0003676	molecular_function	nucleic acid binding
z	0003723	molecular_function	RNA binding
z	0003729	molecular_function	mRNA binding
z	0005515	molecular_function	protein binding
z	0005634	cellular_component	nucleus
z	0005654	cellular_component	nucleoplasm
z	0005681	cellular_component	spliceosomal complex
z	0005684	cellular_component	U2-type spliceosomal complex
z	0005689	cellular_component	U12-type spliceosomal complex
z	0006397	biological_process	mRNA processing
z	0008380	biological_process	RNA splicing
z	1903241	biological_process	U2-type prespliceosome assembly

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cnv..CdcvVkdsinfldHingkkH

Chain	Residue	Details
N	CYS82-HIS104

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH

Chain	Residue	Details
E	PHE287-HIS293

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LASAgfDrLILLWNV

Chain	Residue	Details
D	LEU81-VAL95
D	LEU124-SER138
D	VAL167-ILE181
D	ILE208-LEU222
D	ILE300-THR314
G	LEU303-VAL317
G	ILE345-LEU359

---

site_id	PS00997
Number of Residues	23
Details	G10_1 G10 protein signature 1. LCClRCiqtrDtNfgtnCiCRVP

Chain	Residue	Details
Q	LEU100-PRO122

---

site_id	PS00998
Number of Residues	10
Details	G10_2 G10 protein signature 2. CtHCGCRGCS

Chain	Residue	Details
Q	CYS134-SER143

---

site_id	PS01159
Number of Residues	26
Details	WW_DOMAIN_1 WW/rsp5/WWP domain signature. WteyktadgktyYYnnrtle.STWEKP

Chain	Residue	Details
A4	TRP435-PRO460

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	212
Details	Domain: {"description":"MIF4G"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	153
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	13
Details	Region: {"description":"Interaction with pre-mRNA branch site"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	61
Details	Zinc finger: {"description":"Matrin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00130","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	78
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	78
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	79
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	78
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	79
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	77
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	71
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	21
Details	Repeat: {"description":"LRR 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	21
Details	Repeat: {"description":"LRR 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	21
Details	Repeat: {"description":"LRR 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	21
Details	Repeat: {"description":"LRR 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	38
Details	Domain: {"description":"LRRCT"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	79
Details	Domain: {"description":"RRM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	74
Details	Domain: {"description":"RRM 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	183
Details	Domain: {"description":"Helicase ATP-binding 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	237
Details	Domain: {"description":"Helicase C-terminal 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	305
Details	Domain: {"description":"SEC63 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	175
Details	Domain: {"description":"Helicase ATP-binding 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	208
Details	Domain: {"description":"Helicase C-terminal 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	312
Details	Domain: {"description":"SEC63 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	3
Details	Motif: {"description":"DEIH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	3
Details	Motif: {"description":"DEVH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23045696","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4F93","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"F1LNJ2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q6P4T2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	8
Details	Region: {"description":"Interaction with AR","evidences":[{"source":"PubMed","id":"28076346","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	21
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12374755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12434151","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	9
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	2
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	51
Details	Domain: {"description":"HTH myb-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00625","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	45
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00625","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	509
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2007","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Matallanas D.","Cooper W.N.","Kolch W."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	20
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	77
Details	Region: {"description":"Interaction with SF3B1 and SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	3
Details	Region: {"description":"Interaction with SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28541300","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IFE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SYB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	4
Details	Site: {"description":"Interaction with SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	8
Details	Site: {"description":"Interaction with RNA","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"P83870","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	131
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	491
Details	Region: {"description":"Reverse transcriptase homology domain"}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	171
Details	Region: {"description":"Restriction endonuclease homology domain"}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	34
Details	Region: {"description":"Required for interaction with EFTUD2 and SNRNP200","evidences":[{"source":"PubMed","id":"17317632","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	1
Details	Modified residue: {"description":"N6,N6-dimethyllysine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	27
Details	Zinc finger: {"description":"C3H1-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00723","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	42
Details	Repeat: {"description":"SURP motif 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	Site: {"description":"Critical for binding to SF3A3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	4
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"21349847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI68
Number of Residues	54
Details	Domain: {"description":"FF 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI69
Number of Residues	56
Details	Domain: {"description":"FF 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI70
Number of Residues	56
Details	Domain: {"description":"FF 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI71
Number of Residues	65
Details	Domain: {"description":"FF 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI72
Number of Residues	39
Details	Repeat: {"description":"HEAT 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI73
Number of Residues	34
Details	Repeat: {"description":"HEAT 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI74
Number of Residues	37
Details	Repeat: {"description":"HEAT 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	34
Details	Repeat: {"description":"HEAT 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI76
Number of Residues	38
Details	Repeat: {"description":"HEAT 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	38
Details	Repeat: {"description":"HEAT 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI78
Number of Residues	38
Details	Repeat: {"description":"HEAT 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	38
Details	Repeat: {"description":"HEAT 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	38
Details	Repeat: {"description":"HEAT 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI81
Number of Residues	38
Details	Repeat: {"description":"HEAT 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI82
Number of Residues	38
Details	Repeat: {"description":"HEAT 11"}

Chain

Residue

Details

---

site_id	SWS_FT_FI83
Number of Residues	39
Details	Region: {"description":"Interaction with SF3B14"}

Chain

Residue

Details

---

site_id	SWS_FT_FI84
Number of Residues	4
Details	Region: {"description":"Interaction with PHF5A","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI85
Number of Residues	56
Details	Region: {"description":"Interaction with SF3B3 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI86
Number of Residues	1
Details	Site: {"description":"Interaction with PHF5A","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI87
Number of Residues	1
Details	Modified residue: {"description":"Symmetric dimethylarginine; by PRMT9; alternate","evidences":[{"source":"PubMed","id":"25737013","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI88
Number of Residues	37
Details	Region: {"description":"Interaction with PHF5A, SF3B1 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI89
Number of Residues	56
Details	Region: {"description":"Interaction with SF3B1 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI90
Number of Residues	21
Details	Region: {"description":"Interaction with SF3B1","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI91
Number of Residues	23
Details	Region: {"description":"Interaction with SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI92
Number of Residues	5
Details	Site: {"description":"Interaction with SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI93
Number of Residues	2
Details	Site: {"description":"Interaction with SF3B1","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI94
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI95
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI96
Number of Residues	63
Details	Domain: {"description":"FHA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00086","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI97
Number of Residues	24
Details	Zinc finger: {"description":"Matrin-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI98
Number of Residues	282
Details	Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI99
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI100
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI101
Number of Residues	79
Details	Region: {"description":"Sufficient for interaction with CLNS1A","evidences":[{"source":"PubMed","id":"11747828","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI102
Number of Residues	72
Details	Domain: {"description":"Ubiquitin-like"}

Chain

Residue

Details

---

site_id	SWS_FT_FI103
Number of Residues	9
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---