7ABI

Human pre-Bact-2 spliceosome

Summary for 7ABI

• Entry DOI: 10.2210/pdb7abi/pdb
• Related: 7AAV 7ABF 7ABG 7ABH
• EMDB information: 11693 11694 11695 11696 11697
• Descriptor: U5 small nuclear ribonucleoprotein 40 kDa protein, U2 small nuclear ribonucleoprotein B'', Splicing factor 3B subunit 6, ... (52 entities in total)
• Functional Keywords: complex, spliceosome, catalytic activation, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 56
• Total formula weight: 3129426.49

Authors

Townsend, C.,Kastner, B.,Leelaram, M.N.,Bertram, K.,Stark, H.,Luehrmann, R. (deposition date: 2020-09-07, release date: 2021-02-10)

• Primary citation: Townsend, C.,Leelaram, M.N.,Agafonov, D.E.,Dybkov, O.,Will, C.L.,Bertram, K.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R.; Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.; Science, 370:-, 2020; PubMed: 33243851; DOI: 10.1126/science.abc3753

Experimental method

ELECTRON MICROSCOPY (8 Å)