6T7F

RCR E3 ligase E2-Ubiquitin transthiolation intermediate

Summary for 6T7F

• Entry DOI: 10.2210/pdb6t7f/pdb
• Descriptor: E3 ubiquitin-protein ligase MYCBP2, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-C, ... (6 entities in total)
• Functional Keywords: ring-cys-relay, rcr, activity based probe, ubiquitination, threonine e3 ligase., ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 55222.31

Authors

Mabbitt, P.D.,Virdee, S. (deposition date: 2019-10-21, release date: 2020-08-05, Last modification date: 2024-01-24)

• Primary citation: Mabbitt, P.D.,Loreto, A.,Dery, M.A.,Fletcher, A.J.,Stanley, M.,Pao, K.C.,Wood, N.T.,Coleman, M.P.,Virdee, S.; Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.; Nat.Chem.Biol., 16:1227-1236, 2020; PubMed: 32747811; DOI: 10.1038/s41589-020-0598-6

Experimental method

X-RAY DIFFRACTION (2.58 Å)