6T7F
RCR E3 ligase E2-Ubiquitin transthiolation intermediate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | E3 ubiquitin-protein ligase MYCBP2 | polymer | 261 | 29410.9 | 1 | UniProt (O75592) In PDB | Homo sapiens (Human) | Myc-binding protein 2,Protein associated with Myc |
2 | B | Ubiquitin-conjugating enzyme E2 D3 | polymer | 150 | 16895.2 | 1 | UniProt (P61077) Pfam (PF00179) In PDB | Homo sapiens (Human) | (E3-independent) E2 ubiquitin-conjugating enzyme D3,E2 ubiquitin-conjugating enzyme D3,Ubiquitin carrier protein D3,Ubiquitin-conjugating enzyme E2(17)KB 3,Ubiquitin-conjugating enzyme E2-17 kDa 3,Ubiquitin-protein ligase D3 |
3 | C | Polyubiquitin-C | polymer | 73 | 8305.5 | 1 | UniProt (P0CG48) Pfam (PF00240) In PDB | Homo sapiens (Human) | |
4 | A | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
5 | B | 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide | non-polymer | 218.3 | 1 | Chemie (LWZ) | |||
6 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A: 4385 - 4640 (UniProt: O75592)
B: 2 - 147 (UniProt: P61077)
PDB | External Database | Details |
---|---|---|
Gly 4380 | - | expression tag |
Pro 4381 | - | expression tag |
Leu 4382 | - | expression tag |
Gly 4383 | - | expression tag |
Ser 4384 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
Gly 0 | - | expression tag |
Ser 1 | - | expression tag |
Ser 21 | Cys 21 | engineered mutation |
Arg 22 | Ser 22 | engineered mutation |
Ser 107 | Cys 107 | engineered mutation |
Ser 111 | Cys 111 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 54611.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 610.8 | |
All* | Total formula weight | 55222.3 |