2YJD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yjd by Molmil](/molmil-images/mine/2yjd) | Stapled peptide bound to Estrogen Receptor Beta | 分子名称: | 4-(2-PROPAN-2-YLOXYBENZIMIDAZOL-1-YL)PHENOL, ESTROGEN RECEPTOR BETA, STAPLED PEPTIDE | 著者 | Phillips, C, Roberts, L.R, Schade, M, Bent, A, Davies, N.L, Moore, R, Pannifer, A.D, Brown, D.G, Pickford, A.R, Irving, S.L. | 登録日 | 2011-05-19 | 公開日 | 2011-08-03 | 最終更新日 | 2017-01-25 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Design and Structure of Stapled Peptides Binding to Estrogen Receptors. J.Am.Chem.Soc., 133, 2011
|
|
5LCW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lcw by Molmil](/molmil-images/mine/5lcw) | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | Alfieri, C, Chang, L, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | 登録日 | 2016-06-22 | 公開日 | 2016-08-10 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Molecular basis of APC/C regulation by the spindle assembly checkpoint. Nature, 536, 2016
|
|
2YLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yly by Molmil](/molmil-images/mine/2yly) | Sulfonamides as selective Estrogen Receptor beta Agonists. | 分子名称: | ESTROGEN RECEPTOR BETA, N-cyclopropyl-4-oxidanyl-N-[(2R)-2-oxidanyl-2-phenyl-propyl]benzenesulfonamide, SULFATE ION | 著者 | Roberts, L.R, Armour, D, Barker, C, Bazin, R, Bess, K, Brown, A, Favor, D, Ellis, D, MacKenny, M, Pullen, N, Stennett, A, Strand, L, Styles, M, Phillips, C. | 登録日 | 2011-06-06 | 公開日 | 2012-06-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Sulfonamides as Selective Oestrogen Receptor Beta Agonists. Bioorg.Med.Chem.Lett., 21, 2011
|
|
7JR7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jr7 by Molmil](/molmil-images/mine/7jr7) | Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4 | 分子名称: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, Fab 11F4 heavy chain, ... | 著者 | Huang, C.S, Yu, X, Min, X, Wang, Z, Zhang, H. | 登録日 | 2020-08-11 | 公開日 | 2021-04-07 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies Commun Biol, 4, 2021
|
|
2DS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ds2 by Molmil](/molmil-images/mine/2ds2) | Crystal structure of mabinlin II | 分子名称: | ACETIC ACID, Sweet protein mabinlin-2 chain A, Sweet protein mabinlin-2 chain B | 著者 | Li, D.F, Zhu, D.Y, Wang, D.C. | 登録日 | 2006-06-19 | 公開日 | 2007-06-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of Mabinlin II: a novel structural type of sweet proteins and the main structural basis for its sweetness. J.Struct.Biol., 162, 2008
|
|
5LJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ljj by Molmil](/molmil-images/mine/5ljj) | Crystal structure of human Mps1 (TTK) in complex with Reversine | 分子名称: | 1,2-ETHANEDIOL, Dual specificity protein kinase TTK, N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine | 著者 | Hiruma, Y, Joosten, R.P, Perrakis, A. | 登録日 | 2016-07-18 | 公開日 | 2016-10-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinase. Proteins, 84, 2016
|
|
5M6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5m6o by Molmil](/molmil-images/mine/5m6o) | Frutapin complexed with alpha-D-mannose | 分子名称: | Frutapin, alpha-D-mannopyranose | 著者 | de Sousa, F.D, Guo, J, Coker, A.R, de Oliveira Monteiro-Moreira, A, de Azevedo Moreira, R. | 登録日 | 2016-10-25 | 公開日 | 2017-07-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Frutapin, a lectin fromArtocarpus incisa(breadfruit): cloning, expression and molecular insights. Biosci. Rep., 37, 2017
|
|
5MAS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mas by Molmil](/molmil-images/mine/5mas) | Peptaibol Bergofungin A | 分子名称: | Bergofungin A | 著者 | Gessmann, R, Petratos, K. | 登録日 | 2016-11-04 | 公開日 | 2017-02-22 | 最終更新日 | 2017-03-01 | 実験手法 | X-RAY DIFFRACTION (0.84 Å) | 主引用文献 | A natural, single-residue substitution yields a less active peptaibiotic: the structure of bergofungin A at atomic resolution. Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
2Z14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z14 by Molmil](/molmil-images/mine/2z14) | Crystal structure of the N-terminal DUF1126 in human ef-hand domain containing 2 protein | 分子名称: | EF-hand domain-containing family member C2 | 著者 | Saito, K, Olsen, S, Kishishita, S, Nishino, A, Murayama, K, Terada, T, Shirouzu, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-08 | 公開日 | 2007-11-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Crystal structure of the N-terminal DUF1126 in human ef-hand domain containing 2 protein To be Published
|
|
5LEF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lef by Molmil](/molmil-images/mine/5lef) | Rab6A:Kif20A complex | 分子名称: | GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ISOPROPYL ALCOHOL, ... | 著者 | Bressanelli, G, Pylypenko, O, Houdusse, A. | 登録日 | 2016-06-29 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.088 Å) | 主引用文献 | Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions. Nat Commun, 8, 2017
|
|
2YLE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yle by Molmil](/molmil-images/mine/2yle) | Crystal structure of the human Spir-1 KIND FSI domain in complex with the FSI peptide | 分子名称: | FORMIN-2, PROTEIN SPIRE HOMOLOG 1 | 著者 | Zeth, K, Pechlivanis, M, Vonrhein, C, Kerkhoff, E. | 登録日 | 2011-06-01 | 公開日 | 2011-06-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular Basis of Actin Nucleation Factor Cooperativity: Crystal Structure of the Spir-1 Kinase Non-Catalytic C-Lobe Domain (Kind)Formin-2 Formin Spir Interaction Motif (Fsi) Complex. J.Biol.Chem., 286, 2011
|
|
2YUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yur by Molmil](/molmil-images/mine/2yur) | Solution structure of the Ring finger of human Retinoblastoma-binding protein 6 | 分子名称: | Retinoblastoma-binding protein 6, ZINC ION | 著者 | Abe, H, Miyamoto, K, Tochio, N, Tomizawa, T, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-06 | 公開日 | 2008-04-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Ring finger of human Retinoblastoma-binding protein 6 To be Published
|
|
4USF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4usf by Molmil](/molmil-images/mine/4usf) | Human SLK with SB-440719 | 分子名称: | 4-[4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl]pyridine, STE20-LIKE SERINE/THREONINE-PROTEIN KINASE | 著者 | Elkins, J.M, Salah, E, Szklarz, M, von Delft, F, Bountra, C, Edwards, A.M, Knapp, S. | 登録日 | 2014-07-07 | 公開日 | 2015-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Comprehensive Characterization of the Published Kinase Inhibitor Set. Nat.Biotechnol., 34, 2016
|
|
5LHY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lhy by Molmil](/molmil-images/mine/5lhy) | PB3 Domain of Human PLK4 (apo) | 分子名称: | Serine/threonine-protein kinase PLK4 | 著者 | Cottee, M.A, Johnson, S, Lea, S.M. | 登録日 | 2016-07-13 | 公開日 | 2017-03-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies. Biol Open, 6, 2017
|
|
5LIK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lik by Molmil](/molmil-images/mine/5lik) | Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK181 | 分子名称: | 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Fanfrlik, J, Kamlar, M, Vesely, J, Hobza, P, Podjarny, A. | 登録日 | 2016-07-14 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. Acs Chem.Biol., 11, 2016
|
|
5LIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5liy by Molmil](/molmil-images/mine/5liy) | Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK204 | 分子名称: | 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Fanfrlik, J, Kamlar, M, Vesely, J, Hobza, P, Podjarny, A. | 登録日 | 2016-07-15 | 公開日 | 2016-10-12 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. Acs Chem.Biol., 11, 2016
|
|
5M63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5m63 by Molmil](/molmil-images/mine/5m63) | Crystal structure of group B Streptococcus type III DP2 oligosaccharide bound to Fab NVS-1-19-5 | 分子名称: | (2~{R},3~{R},4~{S},5~{S})-2-[bis(oxidanyl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol, 1,2-ETHANEDIOL, H chain of Fab NVS-1-19-5, ... | 著者 | Carboni, F, Adamo, R, Veggi, D, Rappuoli, R, Malito, E, Margarit, I.R, Berti, F. | 登録日 | 2016-10-24 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
7L0Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l0y by Molmil](/molmil-images/mine/7l0y) | |
5MAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mae by Molmil](/molmil-images/mine/5mae) | CATHEPSIN L IN COMPLEX WITH (2S,4R)-4-(2-Chloro-4-methoxy-benzenesulfonyl)-1-[3-(5-chloro-pyridin-2-yl)-azetidine-3-carbonyl]-pyrrolidine-2-car boxylic acid (1-cyano-cyclopropyl)-amide | 分子名称: | 1,2-ETHANEDIOL, Cathepsin L1, [4-[cyclopentyl(pyrazin-2-ylmethyl)amino]-6-morpholin-4-yl-1,3,5-triazin-2-yl]methylideneazanide | 著者 | Kuglstatter, A, Stihle, M, Benz, J. | 登録日 | 2016-11-03 | 公開日 | 2017-01-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Inhibition of the Cysteine Protease Human Cathepsin L by Triazine Nitriles: AmideHeteroarene pi-Stacking Interactions and Chalcogen Bonding in the S3 Pocket. ChemMedChem, 12, 2017
|
|
7L0X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l0x by Molmil](/molmil-images/mine/7l0x) | |
5MND
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mnd by Molmil](/molmil-images/mine/5mnd) | |
7L0U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l0u by Molmil](/molmil-images/mine/7l0u) | |
7L0V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l0v by Molmil](/molmil-images/mine/7l0v) | |
5MO4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mo4 by Molmil](/molmil-images/mine/5mo4) | |
7L0W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l0w by Molmil](/molmil-images/mine/7l0w) | |