2YLE

Crystal structure of the human Spir-1 KIND FSI domain in complex with the FSI peptide

Summary for 2YLE

• Entry DOI: 10.2210/pdb2yle/pdb
• Related: 2YLF
• Descriptor: PROTEIN SPIRE HOMOLOG 1, FORMIN-2 (3 entities in total)
• Functional Keywords: actin-binding protein, actin polymerization
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm, cytoskeleton: Q08AE8
• Total number of polymer chains: 2
• Total formula weight: 29179.90

Authors

Zeth, K.,Pechlivanis, M.,Vonrhein, C.,Kerkhoff, E. (deposition date: 2011-06-01, release date: 2011-06-08, Last modification date: 2012-08-15)

• Primary citation: Zeth, K.,Pechlivanis, M.,Samol, A.,Pleiser, S.,Vonrhein, C.,Kerkhoff, E.; Molecular Basis of Actin Nucleation Factor Cooperativity: Crystal Structure of the Spir-1 Kinase Non-Catalytic C-Lobe Domain (Kind)Formin-2 Formin Spir Interaction Motif (Fsi) Complex.; J.Biol.Chem., 286:30732-, 2011; PubMed: 21705804; DOI: 10.1074/JBC.M111.257782

Experimental method

X-RAY DIFFRACTION (1.8 Å)