5LHY

PB3 Domain of Human PLK4 (apo)

Summary for 5LHY

Entry DOI	10.2210/pdb5lhy/pdb
Descriptor	Serine/threonine-protein kinase PLK4 (1 entity in total)
Functional Keywords	polo box domain, centriole, transferase, structural protein
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole : O00444
Total number of polymer chains	60
Total formula weight	594911.46
Authors	Cottee, M.A.,Johnson, S.,Lea, S.M. (deposition date: 2016-07-13, release date: 2017-03-01, Last modification date: 2024-01-10)
Primary citation	Cottee, M.A.,Johnson, S.,Raff, J.W.,Lea, S.M. A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies. Biol Open, 6:381-389, 2017 Cited by PubMed: 28202467 DOI: 10.1242/bio.024661 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.31 Å)

Structure validation