7T0R
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![BU of 7t0r by Molmil](/molmil-images/mine/7t0r) | Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adnectin 6940_B01, Ibalizumab Heavy Chain, ... | 著者 | Williams, S.P, Concha, N.O, Wensel, D.L, Hong, X. | 登録日 | 2021-11-30 | 公開日 | 2022-01-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment. J.Mol.Biol., 434, 2021
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7T10
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7T11
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7W5R
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![BU of 7w5r by Molmil](/molmil-images/mine/7w5r) | KRAS G12V and peptide complex | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, LEU-TYR-ASP-VAL-ALA, ... | 著者 | Kim, H.J, Han, C.W, Jang, S.B. | 登録日 | 2021-11-30 | 公開日 | 2022-12-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.87 Å) | 主引用文献 | Structural basis of the oncogenic KRAS mutant and GJ101 complex. Biochem.Biophys.Res.Commun., 641, 2023
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7W5D
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7W5C
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![BU of 7w5c by Molmil](/molmil-images/mine/7w5c) | Crystal structure of Mitogen Activated Protein Kinase 4 (MPK4) from Arabidopsis thaliana | 分子名称: | MAGNESIUM ION, Mitogen-activated protein kinase 4, Mitogen-activated protein kinase kinase 1, ... | 著者 | Arold, S.T, Hameed, U.F.S. | 登録日 | 2021-11-30 | 公開日 | 2022-12-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Essential role of the CD docking motif of MPK4 in plant immunity, growth, and development. New Phytol., 239, 2023
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7W5Z
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![BU of 7w5z by Molmil](/molmil-images/mine/7w5z) | Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-oxoglutarate/malate carrier protein, CARDIOLIPIN, ... | 著者 | Zhou, L, Maldonado, M, Padavannil, A, Letts, J. | 登録日 | 2021-11-30 | 公開日 | 2022-04-06 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism. Science, 376, 2022
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7T0V
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![BU of 7t0v by Molmil](/molmil-images/mine/7t0v) | CryoEM structure of the crosslinked Rix7 AAA-ATPase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | 登録日 | 2021-11-30 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly. Pnas Nexus, 1, 2022
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7W51
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7W4Z
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7W50
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7W52
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7W57
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![BU of 7w57 by Molmil](/molmil-images/mine/7w57) | Cryo-EM structure of the neuromedin S-bound neuromedin U receptor 2-Gq protein complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | 著者 | You, C, Xu, H.E, Jiang, Y. | 登録日 | 2021-11-29 | 公開日 | 2022-04-20 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
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7W56
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![BU of 7w56 by Molmil](/molmil-images/mine/7w56) | Cryo-EM structure of the neuromedin S-bound neuromedin U receptor 1-Gq protein complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | 著者 | You, C, Xu, H.E, Jiang, Y. | 登録日 | 2021-11-29 | 公開日 | 2022-04-20 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
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7W55
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![BU of 7w55 by Molmil](/molmil-images/mine/7w55) | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 2-Gq protein complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | 著者 | You, C, Xu, H.E, Jiang, Y. | 登録日 | 2021-11-29 | 公開日 | 2022-04-20 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
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7W53
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![BU of 7w53 by Molmil](/molmil-images/mine/7w53) | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 1-Gq protein complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | 著者 | You, C, Xu, H.E, Jiang, Y. | 登録日 | 2021-11-29 | 公開日 | 2022-04-20 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
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7SZR
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![BU of 7szr by Molmil](/molmil-images/mine/7szr) | NIK bound to inhibitor G02792917 | 分子名称: | 1-(3-{[(1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2-azabicyclo[3.1.0]hexan-4-yl]ethynyl}phenyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION | 著者 | Liau, N.P.D, Hymowitz, S.G. | 登録日 | 2021-11-29 | 公開日 | 2023-06-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design. Bioorg.Med.Chem.Lett., 89, 2023
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7W5B
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![BU of 7w5b by Molmil](/molmil-images/mine/7w5b) | The cryo-EM structure of human C* complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2021-11-29 | 公開日 | 2022-06-22 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W5A
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![BU of 7w5a by Molmil](/molmil-images/mine/7w5a) | The cryo-EM structure of human pre-C*-II complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2021-11-29 | 公開日 | 2022-06-22 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W59
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![BU of 7w59 by Molmil](/molmil-images/mine/7w59) | The cryo-EM structure of human pre-C*-I complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2021-11-29 | 公開日 | 2022-06-22 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W4P
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![BU of 7w4p by Molmil](/molmil-images/mine/7w4p) | The structure of KATP H175K mutant in closed state | 分子名称: | 6-chloranyl-~{N}-(1-methylcyclopropyl)-1,1-bis(oxidanylidene)-4~{H}-thieno[3,2-e][1,2,4]thiadiazin-3-amine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Chen, L, Wang, M. | 登録日 | 2021-11-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural insights into the mechanism of pancreatic K ATP channel regulation by nucleotides. Nat Commun, 13, 2022
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7W4O
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![BU of 7w4o by Molmil](/molmil-images/mine/7w4o) | The structure of KATP H175K mutant in pre-open state | 分子名称: | 6-chloranyl-~{N}-(1-methylcyclopropyl)-1,1-bis(oxidanylidene)-4~{H}-thieno[3,2-e][1,2,4]thiadiazin-3-amine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Chen, L, Wang, M. | 登録日 | 2021-11-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Structural insights into the mechanism of pancreatic K ATP channel regulation by nucleotides. Nat Commun, 13, 2022
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7QDP
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7QDE
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7W46
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