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PDB: 8 results
7NBI
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BU of 7nbi by Molmil
Crystal structure of a monomeric FLT3 Ligand variant
Descriptor: Fms-related tyrosine kinase 3 ligand, SULFATE ION
Authors:Pannecoucke, E, Raes, L, Savvides, S.N.
Deposit date:2021-01-26
Release date:2021-04-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Engineering and crystal structure of a monomeric FLT3 ligand variant.
Acta Crystallogr.,Sect.F, 77, 2021
7ZV9
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BU of 7zv9 by Molmil
Crystal structure of FLT3 in complex with a monomeric FLT3 Ligand variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fms-related tyrosine kinase 3 ligand, ...
Authors:Pannecoucke, E, Savvides, S.N.
Deposit date:2022-05-14
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4.507 Å)
Cite:Crystal structure of FLT3 in complex with a monomeric FLT3 Ligand variant
To Be Published
6ZIE
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BU of 6zie by Molmil
Crystal structure of MCL-1 in complex with a neutralizing Alphabody CMPX-383B
Descriptor: CMPX-383B, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION
Authors:Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I.
Deposit date:2020-06-25
Release date:2021-04-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Sci Adv, 7, 2021
6ZL1
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BU of 6zl1 by Molmil
Crystal structure of human serum albumin in complex with the MCL-1 neutralizing Alphabody CMPX-383B
Descriptor: Albumin, CMPX-383B
Authors:Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I.
Deposit date:2020-06-30
Release date:2021-04-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.272 Å)
Cite:Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Sci Adv, 7, 2021
7Q15
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BU of 7q15 by Molmil
Crystal structure of FcRn and beta-2-microglobulin in complex with IgG1-Fc-MST-HN (efgartigimod)
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, IgG1-Fc-MST-HN, ...
Authors:Pannecoucke, E, Savvides, S.N.
Deposit date:2021-10-18
Release date:2022-09-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement.
Nat Commun, 13, 2022
7Q3P
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BU of 7q3p by Molmil
Crystal structure of IgG1-Fc-MST-HN (efgartigimod)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Pannecoucke, E, Savvides, S.N.
Deposit date:2021-10-28
Release date:2022-09-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement.
Nat Commun, 13, 2022
7QDP
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BU of 7qdp by Molmil
Crystal structure of FLT3 T343I in complex with the canonical ligand FL
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fms-related tyrosine kinase 3 ligand, ...
Authors:Pannecoucke, E, Savvides, S.N.
Deposit date:2021-11-27
Release date:2022-12-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.691 Å)
Cite:Crystal structure of FLT3 T343I in complex with the canonical ligand FL
To Be Published
7PHS
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BU of 7phs by Molmil
highly potent IL6 antagonistic antibody selected from a camelid immune phage display repertoire
Descriptor: Heavy chain of Fab129D3, Light chain of Fab129D3
Authors:Cambillau, C, Pannecoucke, E, De Haard, H.
Deposit date:2021-08-18
Release date:2022-09-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Non-promiscuous pairing in a highly potent IL6 antagonistic antibody selected from a camelid immune phage display repertoire
To Be Published

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