7T11
CryoEM structure of somatostatin receptor 2 in complex with Octreotide and Gi3.
Summary for 7T11
| Entry DOI | 10.2210/pdb7t11/pdb |
| EMDB information | 25587 |
| Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
| Functional Keywords | gpcr, receptor, complex, membrane protein, membrane protein-signaling protein complex, membrane protein/signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 6 |
| Total formula weight | 160707.77 |
| Authors | Robertson, M.J.,Skinotis, G. (deposition date: 2021-11-30, release date: 2022-03-09, Last modification date: 2022-03-30) |
| Primary citation | Robertson, M.J.,Meyerowitz, J.G.,Panova, O.,Borrelli, K.,Skiniotis, G. Plasticity in ligand recognition at somatostatin receptors. Nat.Struct.Mol.Biol., 29:210-217, 2022 Cited by PubMed: 35210615DOI: 10.1038/s41594-022-00727-5 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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