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7W5A

The cryo-EM structure of human pre-C*-II complex

Summary for 7W5A
Entry DOI10.2210/pdb7w5a/pdb
EMDB information32319
DescriptorPre-mRNA-processing-splicing factor 8, Crooked neck-like protein 1, Pre-mRNA-splicing factor SPF27, ... (49 entities in total)
Functional Keywordsrna splicing, prp22, exon ligation, human spliceosome, c* complex, splicing
Biological sourceHomo sapiens (human)
More
Total number of polymer chains54
Total formula weight2864582.10
Authors
Zhan, X.,Lu, Y.,Shi, Y. (deposition date: 2021-11-29, release date: 2022-06-22, Last modification date: 2022-08-17)
Primary citationZhan, X.,Lu, Y.,Zhang, X.,Yan, C.,Shi, Y.
Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82:2769-2778.e4, 2022
Cited by
PubMed: 35705093
DOI: 10.1016/j.molcel.2022.05.021
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.6 Å)
Structure validation

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