7T10
CryoEM structure of somatostatin receptor 2 in complex with somatostatin-14 and Gi3
Summary for 7T10
Entry DOI | 10.2210/pdb7t10/pdb |
EMDB information | 25586 |
Descriptor | Somatostatin receptor type 2,Kappa-type opioid receptor, Guanine nucleotide-binding protein G(i) subunit alpha-3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total) |
Functional Keywords | gpcr, receptor, complex, membrane protein, membrane protein-signaling protein complex, membrane protein/signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 161327.42 |
Authors | Robertson, M.J.,Skinotis, G. (deposition date: 2021-11-30, release date: 2022-03-09, Last modification date: 2022-03-30) |
Primary citation | Robertson, M.J.,Meyerowitz, J.G.,Panova, O.,Borrelli, K.,Skiniotis, G. Plasticity in ligand recognition at somatostatin receptors. Nat.Struct.Mol.Biol., 29:210-217, 2022 Cited by PubMed: 35210615DOI: 10.1038/s41594-022-00727-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
Download full validation report