7W5B

The cryo-EM structure of human C* complex

This is a non-PDB format compatible entry.

Summary for 7W5B

• Entry DOI: 10.2210/pdb7w5b/pdb
• EMDB information: 32321
• Descriptor: Pre-mRNA-processing-splicing factor 8, Pre-mRNA-splicing factor SYF1, Crooked neck-like protein 1, ... (50 entities in total)
• Functional Keywords: spliceosome, c* complex, rna splicing, prp22, exon ligation, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 55
• Total formula weight: 3127698.94

Authors

Zhan, X.,Lu, Y.,Shi, Y. (deposition date: 2021-11-29, release date: 2022-06-22, Last modification date: 2022-08-17)

• Primary citation: Zhan, X.,Lu, Y.,Zhang, X.,Yan, C.,Shi, Y.; Mechanism of exon ligation by human spliceosome.; Mol.Cell, 82:2769-2778.e4, 2022; PubMed: 35705093; DOI: 10.1016/j.molcel.2022.05.021

Experimental method

ELECTRON MICROSCOPY (4.3 Å)