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PDB: 10 results

2M8D
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BU of 2m8d by Molmil
Structure of SRSF1 RRM2 in complex with the RNA 5'-UGAAGGAC-3'
Descriptor: RNA (5'-R(*UP*GP*AP*AP*GP*GP*AP*C)-3'), Serine/arginine-rich splicing factor 1
Authors:Clery, A, Sinha, R, Anczukow, O, Corrionero, A, Moursy, A, Daubner, G, Valcarcel, J, Krainer, A.R, Allain, F.H.T.
Deposit date:2013-05-17
Release date:2013-07-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
2KXN
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BU of 2kxn by Molmil
NMR structure of human Tra2beta1 RRM in complex with AAGAAC RNA
Descriptor: 5'-R(*AP*AP*GP*AP*AP*C)-3', Transformer-2 protein homolog beta
Authors:Clery, A, Jayne, S, Benderska, N, Dominguez, C, Stamm, S, Allain, F.H.-T.
Deposit date:2010-05-10
Release date:2011-03-16
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-beta1
Nat.Struct.Mol.Biol., 18, 2011
7QDD
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BU of 7qdd by Molmil
NMR structure of Npl3 RRM1 bound to the AUCCAA RNA
Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*A)-3')
Authors:Clery, A, Allain, F.H.-T, Moursy, A.
Deposit date:2021-11-26
Release date:2022-10-26
Last modified:2024-01-10
Method:SOLUTION NMR
Cite:RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.
Nat Commun, 14, 2023
5OR0
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BU of 5or0 by Molmil
NMR derived model of the 5'-splice site of SMN2 in complex with the 5'-end of U1 snRNA
Descriptor: RNA (5'-R(P*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Campagne, S, Clery, A, Allain, F.H.
Deposit date:2017-08-14
Release date:2017-08-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.
Nat Commun, 8, 2017
6HPJ
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BU of 6hpj by Molmil
Structure of human SRSF1 RRM1 bound to AACAAA RNA
Descriptor: Immunoglobulin G-binding protein G,Serine/arginine-rich splicing factor 1, RNA (5'-R(*AP*AP*CP*AP*AP*A)-3')
Authors:Allain, F.T.H, Clery, A.
Deposit date:2018-09-21
Release date:2020-11-18
Last modified:2021-06-02
Method:SOLUTION NMR
Cite:Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing.
Nat Commun, 12, 2021
2MB0
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BU of 2mb0 by Molmil
Solution structure of hnRNP G RRM in complex with the RNA 5'-AUCAAA-3'
Descriptor: RNA-binding motif protein, X chromosome, RNA_(5'-R(*AP*UP*CP*AP*AP*A)-3')
Authors:Moursy, A, Allain, F.H.-T, Clery, A.
Deposit date:2013-07-22
Release date:2014-04-09
Last modified:2014-06-25
Method:SOLUTION NMR
Cite:Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation.
Nucleic Acids Res., 42, 2014
2LEA
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BU of 2lea by Molmil
Solution structure of human SRSF2 (SC35) RRM
Descriptor: Serine/arginine-rich splicing factor 2
Authors:Daubner, G.M, Clery, A, Jayne, S, Stevenin, J, Allain, F.H.-T.
Deposit date:2011-06-15
Release date:2011-11-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
Embo J., 31, 2012
2LEC
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BU of 2lec by Molmil
Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UGGAGU-3'
Descriptor: RNA (5'-R(*UP*GP*GP*AP*GP*U)-3'), Serine/arginine-rich splicing factor 2
Authors:Daubner, G.M, Clery, A, Jayne, S, Stevenin, J, Allain, F.H.-T.
Deposit date:2011-06-15
Release date:2011-11-23
Last modified:2012-05-23
Method:SOLUTION NMR
Cite:A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
Embo J., 31, 2012
2LEB
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BU of 2leb by Molmil
Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UCCAGU-3'
Descriptor: RNA (5'-R(*UP*CP*CP*AP*GP*U)-3'), Serine/arginine-rich splicing factor 2
Authors:Daubner, G.M, Clery, A, Jayne, S, Stevenin, J, Allain, F.H.-T.
Deposit date:2011-06-15
Release date:2011-11-23
Last modified:2012-05-23
Method:SOLUTION NMR
Cite:A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
Embo J., 31, 2012
7QDE
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BU of 7qde by Molmil
NMR structure of Npl3 RRM12 bound to the AUCCAGUGGAA RNA
Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*GP*UP*GP*GP*AP*A)-3')
Authors:Allain, F.H.-T, Clery, A, Moursy, A.
Deposit date:2021-11-26
Release date:2022-12-21
Last modified:2024-01-10
Method:SOLUTION NMR
Cite:RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.
Nat Commun, 14, 2023

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