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2LEB

Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UCCAGU-3'

Summary for 2LEB
Entry DOI10.2210/pdb2leb/pdb
Related2LEA 2LEC
NMR InformationBMRB: 17706
DescriptorSerine/arginine-rich splicing factor 2, RNA (5'-R(*UP*CP*CP*AP*GP*U)-3') (2 entities in total)
Functional Keywordssr protein, splicing factor, rna protein complex, rna binding protein-rna complex, rna binding protein/rna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q01130
Total number of polymer chains2
Total formula weight17110.22
Authors
Daubner, G.M.,Clery, A.,Jayne, S.,Stevenin, J.,Allain, F.H.-T. (deposition date: 2011-06-15, release date: 2011-11-23, Last modification date: 2012-05-23)
Primary citationDaubner, G.M.,Clery, A.,Jayne, S.,Stevenin, J.,Allain, F.H.
A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
Embo J., 31:162-174, 2012
Cited by
PubMed: 22002536
DOI: 10.1038/emboj.2011.367
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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