2LEC
Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UGGAGU-3'
Summary for 2LEC
| Entry DOI | 10.2210/pdb2lec/pdb |
| Related | 2LEA 2LEB |
| NMR Information | BMRB: 17707 |
| Descriptor | Serine/arginine-rich splicing factor 2, RNA (5'-R(*UP*GP*GP*AP*GP*U)-3') (2 entities in total) |
| Functional Keywords | sr protein, splicing factor, rna protein complex, rna binding protein-rna complex, rna binding protein/rna |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: Q01130 |
| Total number of polymer chains | 2 |
| Total formula weight | 17190.27 |
| Authors | Daubner, G.M.,Clery, A.,Jayne, S.,Stevenin, J.,Allain, F.H.-T. (deposition date: 2011-06-15, release date: 2011-11-23, Last modification date: 2012-05-23) |
| Primary citation | Daubner, G.M.,Clery, A.,Jayne, S.,Stevenin, J.,Allain, F.H. A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well. Embo J., 31:162-174, 2012 Cited by PubMed: 22002536DOI: 10.1038/emboj.2011.367 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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