2LEC
Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UGGAGU-3'
Summary for 2LEC
Entry DOI | 10.2210/pdb2lec/pdb |
Related | 2LEA 2LEB |
NMR Information | BMRB: 17707 |
Descriptor | Serine/arginine-rich splicing factor 2, RNA (5'-R(*UP*GP*GP*AP*GP*U)-3') (2 entities in total) |
Functional Keywords | sr protein, splicing factor, rna protein complex, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q01130 |
Total number of polymer chains | 2 |
Total formula weight | 17190.27 |
Authors | Daubner, G.M.,Clery, A.,Jayne, S.,Stevenin, J.,Allain, F.H.-T. (deposition date: 2011-06-15, release date: 2011-11-23, Last modification date: 2024-05-08) |
Primary citation | Daubner, G.M.,Clery, A.,Jayne, S.,Stevenin, J.,Allain, F.H. A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well. Embo J., 31:162-174, 2012 Cited by PubMed: 22002536DOI: 10.1038/emboj.2011.367 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report