3J5Q
| Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy | 分子名称: | Kappa-theraphotoxin-Cg1a 1, Transient receptor potential cation channel subfamily V member 1 | 著者 | Liao, M, Cao, E, Julius, D, Cheng, Y. | 登録日 | 2013-10-28 | 公開日 | 2013-12-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | TRPV1 structures in distinct conformations reveal activation mechanisms. Nature, 504, 2013
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2M9L
| Solution structure of protoxin-1 | 分子名称: | Beta-theraphotoxin-Tp1a | 著者 | Daly, N. | 登録日 | 2013-06-13 | 公開日 | 2014-04-30 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain. Curr.Biol., 24, 2014
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2MPQ
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2MXM
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2MQF
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2MT7
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2MXO
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2N1N
| Solution structure of VSTx1 | 分子名称: | Kappa-theraphotoxin-Gr3a | 著者 | Lau, H.Y, King, G.F, Mobli, M. | 登録日 | 2015-04-12 | 公開日 | 2016-03-02 | 最終更新日 | 2024-10-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels. Sci Rep, 6
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5EPM
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2N6O
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5I1X
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5TLR
| Solution NMR structure of gHwTx-IV | 分子名称: | Mu-theraphotoxin-Hs2a | 著者 | Agwa, A.J, Schroeder, C.I. | 登録日 | 2016-10-11 | 公開日 | 2017-02-22 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7. Biochim. Biophys. Acta, 1859, 2017
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5I2P
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5T3M
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5WE3
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6AV8
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6BTV
| Solution NMR structures for CcoTx-II | 分子名称: | Beta-theraphotoxin-Cm1b | 著者 | Agwa, A.J, Schroeder, C.I. | 登録日 | 2017-12-07 | 公開日 | 2018-05-09 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes. J. Biol. Chem., 293, 2018
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6BR0
| Solution NMR structure for CcoTx-I | 分子名称: | Beta-theraphotoxin-Cm1a | 著者 | Agwa, A.J, Schroeder, C.I. | 登録日 | 2017-11-29 | 公開日 | 2018-05-16 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes. J. Biol. Chem., 293, 2018
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5WLX
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6MK5
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6GFT
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6V6T
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6W6O
| NaChBac-Nav1.7VSDII chimera and HWTX-IV complex | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Huwentoxin-IV, NaChBac-Nav1.7VSDII chimera | 著者 | Yan, N, Gao, S. | 登録日 | 2020-03-17 | 公開日 | 2020-06-24 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na + channels in nanodisc. Proc.Natl.Acad.Sci.USA, 117, 2020
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7K48
| Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera, Mu-theraphotoxin-Hs2a | 著者 | Wisedchaisri, G, Tonggu, L, Gamal El-Din, T.M, McCord, E, Zheng, N, Catterall, W.A. | 登録日 | 2020-09-15 | 公開日 | 2020-12-02 | 最終更新日 | 2021-01-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Basis for High-Affinity Trapping of the Na V 1.7 Channel in Its Resting State by Tarantula Toxin. Mol.Cell, 81, 2021
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8FEY
| Solution structure of Pmu1a | 分子名称: | Pmu1a toxin | 著者 | Daly, N.L, Wilson, D.T. | 登録日 | 2022-12-07 | 公開日 | 2023-03-29 | 最終更新日 | 2023-08-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNa V 1.7 and hCa V 3 voltage-gated channels. Febs J., 290, 2023
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