2MXO
NMR structure of spider toxin- G7W/N24S mutant of TRTX-Hhn2b
Summary for 2MXO
Entry DOI | 10.2210/pdb2mxo/pdb |
Related | 2MQF |
NMR Information | BMRB: 25421 |
Descriptor | Mu-theraphotoxin-Hhn2b (1 entity in total) |
Functional Keywords | spider toxin, voltage gated ion channel, nav1.7, toxin |
Biological source | Haplopelma hainanum (Chinese bird spider) |
Cellular location | Secreted : D2Y1X8 |
Total number of polymer chains | 1 |
Total formula weight | 3793.46 |
Authors | Klint, J.K.,Chin, Y.K.Y.,Mobli, M. (deposition date: 2015-01-08, release date: 2015-12-23, Last modification date: 2023-06-14) |
Primary citation | Klint, J.K.,Chin, Y.K.,Mobli, M. Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7 Mol.Pharmacol., 88:1002-1010, 2015 Cited by PubMed: 26429937DOI: 10.1124/mol.115.100784 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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