5TLR
Solution NMR structure of gHwTx-IV
Summary for 5TLR
| Entry DOI | 10.2210/pdb5tlr/pdb |
| NMR Information | BMRB: 30190 |
| Descriptor | Mu-theraphotoxin-Hs2a (1 entity in total) |
| Functional Keywords | spider toxin, disulfide-rich, sodium channel inhibitor, toxin |
| Biological source | Haplopelma schmidti (Chinese bird spider) |
| Total number of polymer chains | 1 |
| Total formula weight | 4036.82 |
| Authors | Agwa, A.J.,Schroeder, C.I. (deposition date: 2016-10-11, release date: 2017-02-22, Last modification date: 2023-06-14) |
| Primary citation | Agwa, A.J.,Lawrence, N.,Deplazes, E.,Cheneval, O.,Chen, R.M.,Craik, D.J.,Schroeder, C.I.,Henriques, S.T. Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7. Biochim. Biophys. Acta, 1859:835-844, 2017 Cited by PubMed: 28115115DOI: 10.1016/j.bbamem.2017.01.020 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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