2MQF
NMR structure of spider toxin-TRTX-Hhn2b
Summary for 2MQF
| Entry DOI | 10.2210/pdb2mqf/pdb |
| NMR Information | BMRB: 25031 |
| Descriptor | Mu-theraphotoxin-Hhn2b (1 entity in total) |
| Functional Keywords | spider toxin, voltage gated ion channel, nav1.7, toxin |
| Biological source | Haplopelma hainanum (Chinese bird spider) |
| Cellular location | Secreted : D2Y1X8 |
| Total number of polymer chains | 1 |
| Total formula weight | 3691.33 |
| Authors | Klint, J.K.,Chin, Y.K.Y.,Mobli, M. (deposition date: 2014-06-19, release date: 2015-07-15, Last modification date: 2023-06-14) |
| Primary citation | Klint, J.K.,Chin, Y.K.,Mobli, M. Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7 Mol.Pharmacol., 88:1002-1010, 2015 Cited by PubMed: 26429937DOI: 10.1124/mol.115.100784 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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