2MT7

Solution structure of spider-venom peptide Hs1a

Summary for 2MT7

• Entry DOI: 10.2210/pdb2mt7/pdb
• NMR Information: BMRB: 25151
• Descriptor: Hs1a (1 entity in total)
• Functional Keywords: spider-venom peptide, inhibitor cystine knot, nav1.7, nav channel inhibitor, ion channel modulator, toxin
• Biological source: Hysterocrates
• Total number of polymer chains: 1
• Total formula weight: 3866.54

Authors

Klint, J.K.,King, G.F.,Mobli, M. (deposition date: 2014-08-14, release date: 2015-08-19, Last modification date: 2023-06-14)

• Primary citation: Klint, J.K.,Castro, J.,Vetter, I.,Er, S.Y.,Cardoso, F.,Liu, Y.,Hagan, R.,Neff, R.,Minassian, N.,Huang, J.X.,Cooper, M.A.,Wickenden, A.,Mobli, M.,Jin, L.,Nicolazzo, J.A.,Lewis, R.J.,Bosmans, F.,Brierley, S.M.,King, G.F.; Nav1.7 inhibitors normalise mechanical responses in chronic visceral hypersensitivity; To be Published,

Experimental method

SOLUTION NMR