1A0A
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![BU of 1a0a by Molmil](/molmil-images/mine/1a0a) | PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX | 分子名称: | DNA (5'-D(*CP*TP*AP*GP*TP*CP*CP*CP*AP*CP*GP*TP*GP*TP*GP*AP*G )-3'), DNA (5'-D(*CP*TP*CP*AP*CP*AP*CP*GP*TP*GP*GP*GP*AP*CP*TP*AP*G )-3'), PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4) | 著者 | Shimizu, T, Toumoto, A, Ihara, K, Shimizu, M, Kyogoku, Y, Ogawa, N, Oshima, Y, Hakoshima, T. | 登録日 | 1997-11-27 | 公開日 | 1998-03-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition. EMBO J., 16, 1997
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4ATI
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![BU of 4ati by Molmil](/molmil-images/mine/4ati) | MITF:M-box complex | 分子名称: | 5'-D(*AP*GP*GP*GP*TP*CP*AP*TP*GP*TP*GP*CP*TP*AP*AP*C)-3', 5'-D(*GP*TP*TP*AP*GP*CP*AP*CP*AP*TP*GP*AP*CP*CP*CP*T)-3', MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR | 著者 | Pogenberg, V, Deineko, V, Wilmanns, M. | 登録日 | 2012-05-08 | 公開日 | 2012-12-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf Genes Dev., 26, 2012
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4ATH
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![BU of 4ath by Molmil](/molmil-images/mine/4ath) | MITF apo structure | 分子名称: | MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR, SULFATE ION | 著者 | Pogenberg, V, Milewski, M, Wilmanns, M. | 登録日 | 2012-05-08 | 公開日 | 2012-12-12 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf Genes Dev., 26, 2012
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1AN4
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![BU of 1an4 by Molmil](/molmil-images/mine/1an4) | STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF | 分子名称: | DNA (5'-D(*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*C P*TP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*C P*GP*GP*GP*T)-3'), PROTEIN (UPSTREAM STIMULATORY FACTOR) | 著者 | Ferre-D'Amare, A.R, Pognonec, P, Roeder, R.G, Burley, S.K. | 登録日 | 1997-03-15 | 公開日 | 1997-09-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure and function of the b/HLH/Z domain of USF. EMBO J., 13, 1994
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1AM9
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![BU of 1am9 by Molmil](/molmil-images/mine/1am9) | HUMAN SREBP-1A BOUND TO LDL RECEPTOR PROMOTER | 分子名称: | DNA (5'-D(*CP*AP*TP*GP*AP*GP*AP*TP*CP*AP*CP*CP*CP*CP*AP*CP*T P*GP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*CP*AP*GP*TP*GP*GP*GP*GP*TP*GP*AP*TP*CP*T )-3'), MAGNESIUM ION, ... | 著者 | Parraga, A, Burley, S.K. | 登録日 | 1997-06-25 | 公開日 | 1998-07-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution. Structure, 6, 1998
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4ATK
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![BU of 4atk by Molmil](/molmil-images/mine/4atk) | MITF:E-box complex | 分子名称: | 5'-D(*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*T)-3', MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR | 著者 | Pogenberg, V, Deineko, V, Wilmanns, M. | 登録日 | 2012-05-08 | 公開日 | 2012-12-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf Genes Dev., 26, 2012
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4AYA
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![BU of 4aya by Molmil](/molmil-images/mine/4aya) | Crystal structure of ID2 HLH homodimer at 2.1A resolution | 分子名称: | ACETATE ION, DNA-BINDING PROTEIN INHIBITOR ID-2, POTASSIUM ION | 著者 | Wong, M.V, Jiang, S, Palasingam, P, Kolatkar, P.R. | 登録日 | 2012-06-19 | 公開日 | 2012-11-14 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | A Divalent Ion is Crucial in the Structure and Dominant-Negative Function of Id Proteins, a Class of Helix-Loop-Helix Transcription Regulators. Plos One, 7, 2012
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7WZ6
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![BU of 7wz6 by Molmil](/molmil-images/mine/7wz6) | Crystal structure of MyoD-E47 | 分子名称: | Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1 | 著者 | Zhong, J, Huang, Y, Ma, J. | 登録日 | 2022-02-17 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis of the bHLH domains of MyoD-E47 heterodimer. Biochem.Biophys.Res.Commun., 621, 2022
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7Y62
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![BU of 7y62 by Molmil](/molmil-images/mine/7y62) | Crystal structure of human TFEB HLHLZ domain | 分子名称: | Transcription factor EB | 著者 | Yang, G, Li, P, Lin, Y, Liu, Z, Sun, H, Zhao, Z, Fang, P, Wang, J. | 登録日 | 2022-06-18 | 公開日 | 2023-03-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proc.Natl.Acad.Sci.USA, 120, 2023
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7Z5I
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7Z5K
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8IA3
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![BU of 8ia3 by Molmil](/molmil-images/mine/8ia3) | Crystal structure of human USF2 bHLHLZ domain in complex with DNA | 分子名称: | DNA (5'-D(*GP*CP*GP*CP*GP*TP*CP*AP*CP*GP*TP*GP*CP*CP*CP*GP*TP*C)-3'), DNA (5'-D(P*GP*AP*CP*GP*GP*GP*CP*AP*CP*GP*TP*GP*AP*CP*GP*CP*GP*C)-3'), Upstream stimulatory factor 2 | 著者 | Huang, C, Fang, P, Wang, J. | 登録日 | 2023-02-07 | 公開日 | 2023-09-20 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Tetramerization of upstream stimulating factor USF2 requires the elongated bent leucine zipper of the bHLH-LZ domain. J.Biol.Chem., 299, 2023
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8HOV
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8H77
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![BU of 8h77 by Molmil](/molmil-images/mine/8h77) | Hsp90-AhR-p23-XAP2 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | 著者 | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | 登録日 | 2022-10-19 | 公開日 | 2023-01-04 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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8OSB
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![BU of 8osb by Molmil](/molmil-images/mine/8osb) | TWIST1-TCF4-ALX4 complex on specific DNA | 分子名称: | DNA (25-MER), Homeobox protein aristaless-like 4, Transcription factor 4, ... | 著者 | Morgunova, E, Kim, S, Popov, A, Wysocka, J, Taipale, J. | 登録日 | 2023-04-18 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | DNA-guided transcription factor cooperativity shapes face and limb mesenchyme. Cell, 187, 2024
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5Y7Y
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![BU of 5y7y by Molmil](/molmil-images/mine/5y7y) | Crystal structure of AhRR/ARNT complex | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Aryl hydrocarbon receptor repressor, GLYCEROL | 著者 | Sakurai, S, Shimizu, T, Ohto, U. | 登録日 | 2017-08-18 | 公開日 | 2017-09-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription. J. Biol. Chem., 292, 2017
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5NJ8
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5V0L
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![BU of 5v0l by Molmil](/molmil-images/mine/5v0l) | Crystal structure of the AHR-ARNT heterodimer in complex with the DRE | 分子名称: | Aryl hydrocarbon receptor, Aryl hydrocarbon receptor nuclear translocator, CITRIC ACID, ... | 著者 | Seok, S.-H, Lee, W, Jiang, L, Bradfield, C.A, Xing, Y. | 登録日 | 2017-02-28 | 公開日 | 2017-04-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8QMO
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![BU of 8qmo by Molmil](/molmil-images/mine/8qmo) | Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | 著者 | Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J. | 登録日 | 2023-09-24 | 公開日 | 2024-01-10 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds. J.Mol.Biol., 436, 2024
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7ZUB
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![BU of 7zub by Molmil](/molmil-images/mine/7zub) | Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex | 分子名称: | (3~{Z})-3-(3-oxidanylidene-1~{H}-indol-2-ylidene)-1~{H}-indol-2-one, ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, ... | 著者 | Gruszczyk, J, Savva, C.G, Lai-Kee-Him, J, Bous, J, Ancelin, A, Kwong, H.S, Grandvuillemin, L, Bourguet, W. | 登録日 | 2022-05-12 | 公開日 | 2022-11-23 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex. Nat Commun, 13, 2022
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4F3L
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![BU of 4f3l by Molmil](/molmil-images/mine/4f3l) | Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex | 分子名称: | BMAL1b, Circadian locomoter output cycles protein kaput | 著者 | Huang, N, Chelliah, Y, Shan, Y, Taylor, C, Yoo, S, Partch, C, Green, C.B, Zhang, H, Takahashi, J. | 登録日 | 2012-05-09 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.268 Å) | 主引用文献 | Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex. Science, 337, 2012
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5SY5
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![BU of 5sy5 by Molmil](/molmil-images/mine/5sy5) | Crystal Structure of the Heterodimeric NPAS1-ARNT Complex | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 1 | 著者 | Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F. | 登録日 | 2016-08-10 | 公開日 | 2016-11-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | 主引用文献 | NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife, 5, 2016
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5SY7
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![BU of 5sy7 by Molmil](/molmil-images/mine/5sy7) | Crystal Structure of the Heterodimeric NPAS3-ARNT Complex with HRE DNA | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... | 著者 | Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F. | 登録日 | 2016-08-10 | 公開日 | 2016-11-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife, 5, 2016
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2YPA
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![BU of 2ypa by Molmil](/molmil-images/mine/2ypa) | Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA | 分子名称: | EBOX FORWARD, EBOX REVERSE, LIM DOMAIN-BINDING PROTEIN 1, ... | 著者 | El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J. | 登録日 | 2012-10-30 | 公開日 | 2013-07-31 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets. Cell Rep., 4, 2013
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1UKL
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![BU of 1ukl by Molmil](/molmil-images/mine/1ukl) | Crystal structure of Importin-beta and SREBP-2 complex | 分子名称: | Importin beta-1 subunit, Sterol regulatory element binding protein-2 | 著者 | Lee, S.J, Sekimoto, T, Yamashita, E, Nagoshi, E, Nakagawa, A, Imamoto, N, Yoshimura, M, Sakai, H, Tsukihara, T, Yoneda, Y. | 登録日 | 2003-08-26 | 公開日 | 2003-12-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Structure of Importin-beta Bound to SREBP-2: Nuclear Import of a Transcription Factor Science, 302, 2003
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