8IA3

Crystal structure of human USF2 bHLHLZ domain in complex with DNA

Summary for 8IA3

• Entry DOI: 10.2210/pdb8ia3/pdb
• Descriptor: Upstream stimulatory factor 2, DNA (5'-D(P*GP*AP*CP*GP*GP*GP*CP*AP*CP*GP*TP*GP*AP*CP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*CP*GP*TP*CP*AP*CP*GP*TP*GP*CP*CP*CP*GP*TP*C)-3') (3 entities in total)
• Functional Keywords: dna-binding, transcription regulation, transcription/dna, transcription-dna complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 75714.58

Authors

Huang, C.,Fang, P.,Wang, J. (deposition date: 2023-02-07, release date: 2023-09-20, Last modification date: 2023-10-25)

• Primary citation: Huang, C.,Xia, M.,Qiao, H.,Liu, Z.,Lin, Y.,Sun, H.,Yu, B.,Fang, P.,Wang, J.; Tetramerization of upstream stimulating factor USF2 requires the elongated bent leucine zipper of the bHLH-LZ domain.; J.Biol.Chem., 299:105240-105240, 2023; PubMed: 37690682; DOI: 10.1016/j.jbc.2023.105240

Experimental method

X-RAY DIFFRACTION (3.5 Å)