5WEQ
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6VVU
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![BU of 6vvu by Molmil](/molmil-images/mine/6vvu) | Anti-Tryptase fab E104.v1 bound to tryptase | 分子名称: | CALCIUM ION, Fab E104.v1 heavy chain, Fab E104.v1 light chain, ... | 著者 | Ultsch, M, Koerber, J.T. | 登録日 | 2020-02-18 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Bivalent antibody pliers inhibit beta-tryptase by an allosteric mechanism dependent on the IgG hinge. Nat Commun, 11, 2020
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7WR8
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4P59
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![BU of 4p59 by Molmil](/molmil-images/mine/4p59) | HER3 extracellular domain in complex with Fab fragment of MOR09825 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MOR09825 Fab fragment heavy chain, ... | 著者 | Sprague, E.R. | 登録日 | 2014-03-15 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin. Cancer Res., 73, 2013
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5UTZ
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![BU of 5utz by Molmil](/molmil-images/mine/5utz) | Human IL-2/Fab complex | 分子名称: | Fab 5111 heavy chain, Fab 5111 light chain, GLYCEROL, ... | 著者 | Jude, K.M, Garcia, K.C. | 登録日 | 2017-02-15 | 公開日 | 2018-07-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.747 Å) | 主引用文献 | A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism. Nat. Med., 24, 2018
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4EIG
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![BU of 4eig by Molmil](/molmil-images/mine/4eig) | CA1698 camel antibody fragment in complex with DHFR | 分子名称: | CA1698 camel antibody fragment, Dihydrofolate reductase | 著者 | Oyen, D, Srinivasan, V. | 登録日 | 2012-04-05 | 公開日 | 2013-04-24 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
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7FGK
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![BU of 7fgk by Molmil](/molmil-images/mine/7fgk) | The Fab antibody single structure against tau protein. | 分子名称: | Fab Heavy Chain, Fab Light Chain, GLYCEROL, ... | 著者 | Tsuchida, T, Susa, K, Kibiki, T, Tsuchiya, T, Miyamoto, K, In, Y, Minoura, K, Taniguchi, T, Ishida, T, Tomoo, K. | 登録日 | 2021-07-27 | 公開日 | 2022-07-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The free structure of the Fab domain of antibody that recognizes the PHF core region VQIINK in Tau protein. To Be Published
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7FGJ
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![BU of 7fgj by Molmil](/molmil-images/mine/7fgj) | The cross-reaction complex structure with VQILNK peptide and the tau antibody's Fab domain. | 分子名称: | CHLORIDE ION, Fab Heavy Chain, Fab Light Chain, ... | 著者 | Tsuchida, T, Tsuchiya, T, Miyamoto, K, In, Y, Minoura, K, Taniguchi, T, Ishida, T, Tomoo, K. | 登録日 | 2021-07-27 | 公開日 | 2022-07-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | The cross-reaction complex structure with VQILNK peptide and the antibody's Fab domain. To Be Published
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7FGL
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![BU of 7fgl by Molmil](/molmil-images/mine/7fgl) | The complex structure of PHF core domain peptide of tau, VQIVYK, and antibody's Fab domain. | 分子名称: | AMMONIUM ION, Fab Heavy Chain, Fab Light Chain, ... | 著者 | Tsuchida, T, Tsuchiya, T, Miyamoto, K, In, Y, Minoura, K, Taniguchi, T, Ishida, T, Tomoo, K. | 登録日 | 2021-07-27 | 公開日 | 2022-07-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The cross-reaction complex structure with VQIVYK of tau and the antibody's Fab domain. To Be Published
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3AY4
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![BU of 3ay4 by Molmil](/molmil-images/mine/3ay4) | Crystal structure of nonfucosylated Fc complexed with bis-glycosylated soluble form of Fc gamma receptor IIIa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor III-A, ... | 著者 | Mizushima, T, Takemoto, E, Yagi, H, Shibata-Koyama, M, Isoda, Y, Iida, S, Satoh, M, Kato, K. | 登録日 | 2011-04-28 | 公開日 | 2011-08-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans Genes Cells, 16, 2011
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3H3P
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6WIT
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![BU of 6wit by Molmil](/molmil-images/mine/6wit) | Crystal structure of NHP D15.SD7 Fab in complex with 16055 V1V2 1FD6 scaffold | 分子名称: | 16055 V1V2 1FD6 Scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, NHP GN1-SD7 Fab Heavy Chain, ... | 著者 | Liban, T, Aljedani, S, Rodarte, J, Pancera, M. | 登録日 | 2020-04-10 | 公開日 | 2021-04-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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6KN9
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4K3G
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6OGX
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![BU of 6ogx by Molmil](/molmil-images/mine/6ogx) | Ternary complex of OX40R (TNFRSF4) bound to Fab1 and Fab2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1 Heavy Chain, Fab1 Light Chain, ... | 著者 | Ultsch, M.H, Boenig, G, Harris, S.F. | 登録日 | 2019-04-03 | 公開日 | 2019-07-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members. Mabs, 11, 2019
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6OKM
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![BU of 6okm by Molmil](/molmil-images/mine/6okm) | Human OX40R (TNFRSF4) bound to Fab 3C8 | 分子名称: | Fab 3C8 Heavy Chain, Fab 3C8 light chain, Tumor necrosis factor receptor superfamily member 4 | 著者 | Boenig, G, Ultsch, M.H, Harris, S.F. | 登録日 | 2019-04-14 | 公開日 | 2019-08-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members. Mabs, 11, 2019
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6OKN
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![BU of 6okn by Molmil](/molmil-images/mine/6okn) | OX40R (TNFRSF4) bound to Fab 1A7 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fab 1A7 heavy chain, Fab 1A7 light chain, ... | 著者 | Ultsch, M.H, Boenig, G, Harris, S.F. | 登録日 | 2019-04-14 | 公開日 | 2019-07-10 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members. Mabs, 11, 2019
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6XLZ
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![BU of 6xlz by Molmil](/molmil-images/mine/6xlz) | Structure of NHP D11A.F2 Fab in complex with 16055 V2b peptide | 分子名称: | (R,R)-2,3-BUTANEDIOL, Envelope glycoprotein gp160, NHP_D11A.F2_Fab_Heavy_chain, ... | 著者 | Aljedani, S, Rodarte, J, Liban, T, Pancera, M. | 登録日 | 2020-06-29 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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6XSN
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4ZS6
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![BU of 4zs6 by Molmil](/molmil-images/mine/4zs6) | Receptor binding domain and Fab complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein, fab Heavy Chain, ... | 著者 | Yu, X, Wang, X. | 登録日 | 2015-05-13 | 公開日 | 2015-09-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.166 Å) | 主引用文献 | Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27 Sci Rep, 5, 2015
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6YE3
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![BU of 6ye3 by Molmil](/molmil-images/mine/6ye3) | IL-2 in complex with a Fab fragment from UFKA-20 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chains: A,D,G, Chains: B,E,H, ... | 著者 | Karakus, U, Mittl, P, Boyman, O. | 登録日 | 2020-03-23 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species. Sci Transl Med, 12, 2020
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5W6D
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![BU of 5w6d by Molmil](/molmil-images/mine/5w6d) | Crystal structure of BG505-SOSIP.v4.1-GT1-N137A in complex with Fabs 35022 and 9H/109L | 分子名称: | 109L FAB light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Garces, F, Stanfield, R.L, Wilson, I.A. | 登録日 | 2017-06-16 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.202 Å) | 主引用文献 | Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. J. Exp. Med., 214, 2017
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5WKZ
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![BU of 5wkz by Molmil](/molmil-images/mine/5wkz) | VH1-69 germline antibody predicted from CR6261 | 分子名称: | Immunoglobulin heavy variable 1-69D,IgG H chain, Lambda-chain (AA -20 to 215), SULFATE ION | 著者 | Lang, S, Lee, P.S. | 登録日 | 2017-07-25 | 公開日 | 2018-08-01 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem To Be Published
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4LIQ
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![BU of 4liq by Molmil](/molmil-images/mine/4liq) | Structure of the extracellular domain of human CSF-1 receptor in complex with the Fab fragment of RG7155 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment RG7155 heavy chain, Fab fragment RG7155 light chain, ... | 著者 | Benz, J, Gorr, I.H, Hertenberger, H, Ries, C.H. | 登録日 | 2013-07-03 | 公開日 | 2014-06-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy Cancer Cell, 25, 2014
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7RFP
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![BU of 7rfp by Molmil](/molmil-images/mine/7rfp) | Mouse GITR (mGITR) with DTA-1 Fab fragment | 分子名称: | DTA-1 (heavy chain), DTA-1 (light chain), Tumor necrosis factor receptor superfamily member 18,Enhanced green fluorescent protein | 著者 | Meyerson, J.R, He, C. | 登録日 | 2021-07-14 | 公開日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism. Sci Adv, 8, 2022
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