6XSN

Crystal structure of NHP VD20.5A4 Fab in complex with 16055 V1V2 1FD6 scaffold

Summary for 6XSN

• Entry DOI: 10.2210/pdb6xsn/pdb
• Related: 6VJN 6WAS 6WIT 6XLZ
• Descriptor: VD20.5A4_heavy_chain, VD20.5A4_light_chain, 16055_V1V2-1FD6, ... (8 entities in total)
• Functional Keywords: vd20.5a4 fab, antibody, immune system, nhps, fab, 16055 v1v2, 1fd6 scaffold
• Biological source: Macaca mulatta; More
• Total number of polymer chains: 3
• Total formula weight: 63534.53

Authors

Aljedani, S.,Pancera, M. (deposition date: 2020-07-15, release date: 2021-07-21, Last modification date: 2023-10-18)

• Primary citation: Aljedani, S.S.,Liban, T.J.,Tran, K.,Phad, G.,Singh, S.,Dubrovskaya, V.,Pushparaj, P.,Martinez-Murillo, P.,Rodarte, J.,Mileant, A.,Mangala Prasad, V.,Kinzelman, R.,O'Dell, S.,Mascola, J.R.,Lee, K.K.,Karlsson Hedestam, G.B.,Wyatt, R.T.,Pancera, M.; Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.; Plos Pathog., 17:e1009543-e1009543, 2021; PubMed: 34559844; DOI: 10.1371/journal.ppat.1009543

Experimental method

X-RAY DIFFRACTION (2.87 Å)