5W6D
Crystal structure of BG505-SOSIP.v4.1-GT1-N137A in complex with Fabs 35022 and 9H/109L
Summary for 5W6D
Entry DOI | 10.2210/pdb5w6d/pdb |
Descriptor | BG505-SOSIP.v4.1-GT1-N137A gp120, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total) |
Functional Keywords | hiv-1 broadly neutralizing antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 (HIV-1) More |
Total number of polymer chains | 6 |
Total formula weight | 176226.50 |
Authors | Garces, F.,Stanfield, R.L.,Wilson, I.A. (deposition date: 2017-06-16, release date: 2017-07-05, Last modification date: 2023-10-04) |
Primary citation | Medina-Ramirez, M.,Garces, F.,Escolano, A.,Skog, P.,de Taeye, S.W.,Del Moral-Sanchez, I.,McGuire, A.T.,Yasmeen, A.,Behrens, A.J.,Ozorowski, G.,van den Kerkhof, T.L.G.M.,Freund, N.T.,Dosenovic, P.,Hua, Y.,Gitlin, A.D.,Cupo, A.,van der Woude, P.,Golabek, M.,Sliepen, K.,Blane, T.,Kootstra, N.,van Breemen, M.J.,Pritchard, L.K.,Stanfield, R.L.,Crispin, M.,Ward, A.B.,Stamatatos, L.,Klasse, P.J.,Moore, J.P.,Nemazee, D.,Nussenzweig, M.C.,Wilson, I.A.,Sanders, R.W. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. J. Exp. Med., 214:2573-2590, 2017 Cited by PubMed: 28847869DOI: 10.1084/jem.20161160 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.202 Å) |
Structure validation
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