6YE3
IL-2 in complex with a Fab fragment from UFKA-20
Summary for 6YE3
Entry DOI | 10.2210/pdb6ye3/pdb |
Descriptor | Chains: A,D,G, Chains: B,E,H, Interleukin-2, ... (5 entities in total) |
Functional Keywords | il-2, fab, treg, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 9 |
Total formula weight | 268679.94 |
Authors | Karakus, U.,Mittl, P.,Boyman, O. (deposition date: 2020-03-23, release date: 2020-12-30, Last modification date: 2024-01-24) |
Primary citation | Karakus, U.,Sahin, D.,Mittl, P.R.E.,Mooij, P.,Koopman, G.,Boyman, O. Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species. Sci Transl Med, 12:-, 2020 Cited by PubMed: 33328333DOI: 10.1126/scitranslmed.abb9283 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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