6OKM
Human OX40R (TNFRSF4) bound to Fab 3C8
Summary for 6OKM
Entry DOI | 10.2210/pdb6okm/pdb |
Related | 6OGX |
Descriptor | Fab 3C8 Heavy Chain, Fab 3C8 light chain, Tumor necrosis factor receptor superfamily member 4, ... (4 entities in total) |
Functional Keywords | ox40, tnfrsf4, fab, receptor, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 64805.26 |
Authors | |
Primary citation | Yang, Y.,Yeh, S.H.,Madireddi, S.,Matochko, W.L.,Gu, C.,Pacheco Sanchez, P.,Ultsch, M.,De Leon Boenig, G.,Harris, S.F.,Leonard, B.,Scales, S.J.,Zhu, J.W.,Christensen, E.,Hang, J.Q.,Brezski, R.J.,Marsters, S.,Ashkenazi, A.,Sukumaran, S.,Chiu, H.,Cubas, R.,Kim, J.M.,Lazar, G.A. Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members. Mabs, 11:996-1011, 2019 Cited by PubMed: 31156033DOI: 10.1080/19420862.2019.1625662 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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