PDB: 888 件ウェブページステータス検索Chemie searchBIRD

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8FLT	Human PTH1R in complex with M-PTH(1-14) and Gs 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Cary, B.P, Belousoff, M.J, Piper, S.J, Wootten, D, Sexton, P.M. 登録日 2022-12-22 公開日 2023-04-26 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Molecular insights into peptide agonist engagement with the PTH receptor. Structure, 31, 2023
8G94	Structure of CD69-bound S1PR1 coupled to heterotrimeric Gi 分子名称: Early activation antigen CD69, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Chen, H, Li, X. 登録日 2023-02-21 公開日 2023-04-19 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Transmembrane protein CD69 acts as an S1PR1 agonist. Elife, 12, 2023
7YAC	Paltusotine-bound SSTR2-Gi complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Zhao, J, Shao, Z. 登録日 2022-06-27 公開日 2023-04-19 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine. Nat Commun, 14, 2023
7YKD	Cryo-EM structure of the human chemerin receptor 1 complex with the C-terminal nonapeptide of chemerin 分子名称: CHOLESTEROL, Chemerin-like receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Chen, G, Liao, Q, Ye, R.D, Wang, J. 登録日 2022-07-22 公開日 2023-04-19 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Cryo-EM structure of the human chemerin receptor 1-Gi protein complex bound to the C-terminal nonapeptide of chemerin. Proc.Natl.Acad.Sci.USA, 120, 2023
7YAE	Octreotide-bound SSTR2-Gi complex 分子名称: CHOLESTEROL, DPN-CYS-PHE-DTR-LYS-THR-CYS-THO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Zhao, J, Shao, Z. 登録日 2022-06-28 公開日 2023-04-19 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine. Nat Commun, 14, 2023
8FU6	GCGR-Gs complex in the presence of RAMP2 分子名称: Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Krishna Kumar, K, O'Brien, E.S, Wang, H, Montabana, E, Kobilka, B.K. 登録日 2023-01-16 公開日 2023-04-12 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Negative allosteric modulation of the glucagon receptor by RAMP2. Cell, 186, 2023
8IBV	Cryo-EM structure of the motilin-bound motilin receptor-Gq protein complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... 著者 Jiang, Y, Xu, H.E, You, C, Xu, Y. 登録日 2023-02-10 公開日 2023-04-12 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Structural basis for motilin and erythromycin recognition by motilin receptor. Sci Adv, 9, 2023
8IBU	Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex 分子名称: ERYTHROMYCIN A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 You, C, Jiang, Y, Xu, H.E, Xu, Y. 登録日 2023-02-10 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.51 Å) 主引用文献 Structural basis for motilin and erythromycin recognition by motilin receptor. Sci Adv, 9, 2023
8FN1	CryoEM structure of Go-coupled NTSR1 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... 著者 Krumm, B.E, DiBerto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. 登録日 2022-12-26 公開日 2023-03-29 最終更新日 2023-04-19 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
8FMZ	Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, MiniGq, ... 著者 Krumm, B.E, Diberto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. 登録日 2022-12-26 公開日 2023-03-29 最終更新日 2023-04-19 実験手法 ELECTRON MICROSCOPY (2.59 Å) 主引用文献 Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
8FN0	CryoEM structure of Go-coupled NTSR1 with a biased allosteric modulator 分子名称: 2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Krumm, B.E, DiBerto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. 登録日 2022-12-26 公開日 2023-03-29 最終更新日 2023-04-19 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
7YS6	Cryo-EM structure of the Serotonin 6 (5-HT6) receptor-DNGs-scFv16 complex 分子名称: 5-hydroxytryptamine receptor 6, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Zhao, Q.Y, Wang, Y.F, He, L, Wang, S, Cong, Y. 登録日 2022-08-11 公開日 2023-03-29 最終更新日 2023-10-11 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into constitutive activity of 5-HT 6 receptor. Proc.Natl.Acad.Sci.USA, 120, 2023
8I2G	FSHR-Follicle stimulating hormone-compound 716340-Gs complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... 著者 Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. 登録日 2023-01-14 公開日 2023-03-29 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nat Commun, 14, 2023
7F6G	Cryo-EM structure of human angiotensin receptor AT1R in complex Gq proteins and Sar1-AngII 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin receptor AT1R, CHOLESTEROL, ... 著者 Zhang, D, Xu, L, Zhan, Y, Guo, J, Zhang, H. 登録日 2021-06-25 公開日 2023-03-29 最終更新日 2023-10-18 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists. Embo J., 42, 2023
8HCX	Cryo-EM structure of Endothelin1-bound ETBR-Gq complex 分子名称: Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. 登録日 2022-11-03 公開日 2023-03-22 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of peptide recognition and activation of endothelin receptors. Nat Commun, 14, 2023
8HBD	Cryo-EM structure of IRL1620-bound ETBR-Gi complex 分子名称: Endothelin receptor type B,Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Yuan, Q, Ji, Y, Jiang, Y, Duan, J, Xu, H.E. 登録日 2022-10-28 公開日 2023-03-22 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (2.99 Å) 主引用文献 Structural basis of peptide recognition and activation of endothelin receptors. Nat Commun, 14, 2023
8HCQ	Cryo-EM structure of endothelin1-bound ETAR-Gq complex 分子名称: Endothelin-1, Endothelin-1 receptor,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. 登録日 2022-11-02 公開日 2023-03-22 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural basis of peptide recognition and activation of endothelin receptors. Nat Commun, 14, 2023
8F76	Human olfactory receptor OR51E2 bound to propionate in complex with miniGs399 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Billesboelle, C.B, Manglik, A. 登録日 2022-11-18 公開日 2023-03-22 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of odorant recognition by a human odorant receptor. Nature, 615, 2023
7YOO	Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Kang, H, Park, C, Kim, J, Choi, H.-J. 登録日 2022-08-01 公開日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
7YON	Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Kang, H, Park, C, Kim, J, Choi, H.-J. 登録日 2022-08-01 公開日 2023-03-22 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
8HJ2	GPR21 wt with G15 complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X, Xu, F. 登録日 2022-11-22 公開日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HJ0	GPR21(m5) and G15 complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X. 登録日 2022-11-22 公開日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HIX	Cryo-EM structure of GPR21_m5_Gs 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X, Xu, F. 登録日 2022-11-22 公開日 2023-03-15 最終更新日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8ID9	Cryo-EM structure of the eicosapentaenoic acid bound GPR120-Gi complex 分子名称: 5,8,11,14,17-EICOSAPENTAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. 登録日 2023-02-12 公開日 2023-03-15 最終更新日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
8ID3	Cryo-EM structure of the 9-hydroxystearic acid bound GPR120-Gi complex 分子名称: 9-Hydroxyoctadecanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. 登録日 2023-02-12 公開日 2023-03-15 最終更新日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023

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