8I2G
FSHR-Follicle stimulating hormone-compound 716340-Gs complex
Summary for 8I2G
Entry DOI | 10.2210/pdb8i2g/pdb |
EMDB information | 35135 |
Descriptor | chimera of Guanine nucleotide-binding protein G(s) subunit alpha and Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, PALMITIC ACID, MYRISTIC ACID, ... (13 entities in total) |
Functional Keywords | follicle stimulating hormone, fsh, gpcr, gs-protein, hormone |
Biological source | Cricetulus griseus (Chinese hamster) More |
Total number of polymer chains | 7 |
Total formula weight | 196969.02 |
Authors | |
Primary citation | Duan, J.,Xu, P.,Zhang, H.,Luan, X.,Yang, J.,He, X.,Mao, C.,Shen, D.D.,Ji, Y.,Cheng, X.,Jiang, H.,Jiang, Y.,Zhang, S.,Zhang, Y.,Xu, H.E. Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nat Commun, 14:519-519, 2023 Cited by PubMed: 36720854DOI: 10.1038/s41467-023-36170-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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