7F6G

Cryo-EM structure of human angiotensin receptor AT1R in complex Gq proteins and Sar1-AngII

Summary for 7F6G

• Entry DOI: 10.2210/pdb7f6g/pdb
• EMDB information: 31479
• Descriptor: Angiotensin receptor AT1R, SAR1-AngII, Guanine nucleotide-binding protein G(q) subunit alpha, ... (7 entities in total)
• Functional Keywords: gpcr, angiotensin receptor, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 176983.43

Authors

Zhang, D.,Xu, L.,Zhan, Y.,Guo, J.,Zhang, H. (deposition date: 2021-06-25, release date: 2023-03-29, Last modification date: 2023-10-18)

• Primary citation: Zhang, D.,Liu, Y.,Zaidi, S.A.,Xu, L.,Zhan, Y.,Chen, A.,Guo, J.,Huang, X.P.,Roth, B.L.,Katritch, V.,Cherezov, V.,Zhang, H.; Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists.; Embo J., 42:e112940-e112940, 2023; PubMed: 37038975; DOI: 10.15252/embj.2022112940

Experimental method

ELECTRON MICROSCOPY (2.9 Å)