8IBU

Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex

Summary for 8IBU

• Entry DOI: 10.2210/pdb8ibu/pdb
• EMDB information: 35345
• Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv16, ... (6 entities in total)
• Functional Keywords: cryo-em, gpcr, erythromycin, motilin receptor, gq, complex, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 198359.55

Authors

You, C.,Jiang, Y.,Xu, H.E.,Xu, Y. (deposition date: 2023-02-10, release date: 2023-04-12)

• Primary citation: You, C.,Zhang, Y.,Xu, Y.,Xu, P.,Li, Z.,Li, H.,Huang, S.,Chen, Z.,Li, J.,Xu, H.E.,Jiang, Y.; Structural basis for motilin and erythromycin recognition by motilin receptor.; Sci Adv, 9:eade9020-eade9020, 2023; PubMed: 36921049; DOI: 10.1126/sciadv.ade9020

Experimental method

ELECTRON MICROSCOPY (3.51 Å)