7YON

Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi

Summary for 7YON

• Entry DOI: 10.2210/pdb7yon/pdb
• Related: 7YOO
• EMDB information: 33984 35497 35498 35499
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: npy, gpcr, g-protein, complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 161627.81

Authors

Kang, H.,Park, C.,Kim, J.,Choi, H.-J. (deposition date: 2022-08-01, release date: 2023-03-22)

• Primary citation: Kang, H.,Park, C.,Choi, Y.K.,Bae, J.,Kwon, S.,Kim, J.,Choi, C.,Seok, C.,Im, W.,Choi, H.J.; Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling.; Structure, 31:44-57.e6, 2023; PubMed: 36525977; DOI: 10.1016/j.str.2022.11.010

Experimental method

ELECTRON MICROSCOPY (2.95 Å)