7YAC
Paltusotine-bound SSTR2-Gi complex
Summary for 7YAC
Entry DOI | 10.2210/pdb7yac/pdb |
EMDB information | 33708 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | agonist, membrane protein, complex, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 152390.08 |
Authors | |
Primary citation | Zhao, J.,Fu, H.,Yu, J.,Hong, W.,Tian, X.,Qi, J.,Sun, S.,Zhao, C.,Wu, C.,Xu, Z.,Cheng, L.,Chai, R.,Yan, W.,Wei, X.,Shao, Z. Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine. Nat Commun, 14:962-962, 2023 Cited by PubMed: 36810324DOI: 10.1038/s41467-023-36673-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.24 Å) |
Structure validation
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