6YMQ
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![BU of 6ymq by Molmil](/molmil-images/mine/6ymq) | TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Single-chain variable 4, ... | 著者 | Szykowska, A, Preger, C, Scacioc, A, Mukhopadhyay, S.M.M, McKinley, G, Graslund, S, Wigren, E, Persson, H, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Di Daniel, E, Davis, J.B, Burgess-Brown, N, Bullock, A. | 登録日 | 2020-04-09 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain. Structure, 29, 2021
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6YJP
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![BU of 6yjp by Molmil](/molmil-images/mine/6yjp) | Crystal structure of a complex between glycosylated NKp30 and its deglycosylated tumour ligand B7-H6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Natural cytotoxicity triggering receptor 3, Natural cytotoxicity triggering receptor 3 ligand 1 | 著者 | Skalova, T, Dohnalek, J, Skorepa, O, Kalouskova, B, Pazicky, S, Blaha, J, Vanek, O. | 登録日 | 2020-04-04 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N -Glycosylation. Cancers (Basel), 12, 2020
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7BPK
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![BU of 7bpk by Molmil](/molmil-images/mine/7bpk) | Zika virus envelope protein mutant bound to mAb | 分子名称: | Envelope protein, IG c307_light_IGLV1-51_IGLJ2, Z3L1 Heavy chain | 著者 | Dai, L, Qi, J, Gao, G.F. | 登録日 | 2020-03-23 | 公開日 | 2021-03-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nat.Immunol., 22, 2021
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6YCR
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![BU of 6ycr by Molmil](/molmil-images/mine/6ycr) | Structure of human PD-L1 in complex with inhibitor | 分子名称: | FFIVIRDRVFR(CCS)G(NH2), Programmed cell death 1 ligand 1 | 著者 | Magiera-Mularz, K, Grudnik, P, Kuska, K, Holak, T.A, Dubin, G. | 登録日 | 2020-03-18 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Macrocyclic Peptide Inhibitor of PD-1/PD-L1 Immune Checkpoint Adv. Ther., 2020
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6Y6C
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![BU of 6y6c by Molmil](/molmil-images/mine/6y6c) | TREM2 extracellular domain (19-174) in complex with single-chain variable fragment (scFv-4) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Single chain variable, Triggering receptor expressed on myeloid cells 2 | 著者 | Szykowska, A, Preger, C, Williams, E, Mukhopadhyay, S.M.M, McKinley, G, Gruslund, S, Wigren, E, Persson, H, Arrowsmith, C.H, Edwards, A, von Delft, F, Bountra, C, Davis, J.B, Di Daniel, E, Burgess-Brown, N, Bullock, A. | 登録日 | 2020-02-26 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain. Structure, 29, 2021
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6VTU
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![BU of 6vtu by Molmil](/molmil-images/mine/6vtu) | |
6VTT
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![BU of 6vtt by Molmil](/molmil-images/mine/6vtt) | |
6LXW
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![BU of 6lxw by Molmil](/molmil-images/mine/6lxw) | Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA | 分子名称: | Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ... | 著者 | Wang, Y, Wang, G, Li, Y, Xiao, J. | 登録日 | 2020-02-12 | 公開日 | 2020-05-27 | 最終更新日 | 2020-07-22 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin. Cell Res., 30, 2020
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6VSV
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![BU of 6vsv by Molmil](/molmil-images/mine/6vsv) | |
6VSJ
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![BU of 6vsj by Molmil](/molmil-images/mine/6vsj) | Cryo-electron microscopy structure of mouse coronavirus spike protein complexed with its murine receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 1, Spike glycoprotein | 著者 | Shang, J, Wan, Y.S, Liu, C, Yount, B, Gully, K, Yang, Y, Auerbach, A, Peng, G.Q, Baric, R, Li, F. | 登録日 | 2020-02-11 | 公開日 | 2020-03-04 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry. Plos Pathog., 16, 2020
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6LX3
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![BU of 6lx3 by Molmil](/molmil-images/mine/6lx3) | Cryo-EM structure of human secretory immunoglobulin A | 分子名称: | Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor | 著者 | Wang, Y, Wang, G, Li, Y, Xiao, J. | 登録日 | 2020-02-10 | 公開日 | 2020-05-27 | 最終更新日 | 2020-07-22 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin. Cell Res., 30, 2020
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6VRR
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![BU of 6vrr by Molmil](/molmil-images/mine/6vrr) | |
6VRK
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![BU of 6vrk by Molmil](/molmil-images/mine/6vrk) | Cryo-EM structure of the wild-type human serotonin transporter complexed with Br-paroxetine and 8B6 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-02-07 | 公開日 | 2020-03-11 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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6VRH
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![BU of 6vrh by Molmil](/molmil-images/mine/6vrh) | Cryo-EM structure of the wild-type human serotonin transporter complexed with paroxetine and 8B6 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-02-07 | 公開日 | 2020-03-11 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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6VRL
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![BU of 6vrl by Molmil](/molmil-images/mine/6vrl) | Cryo-EM structure of the wild-type human serotonin transporter complexed with I-paroxetine and 8B6 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-02-07 | 公開日 | 2020-03-11 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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6VQN
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![BU of 6vqn by Molmil](/molmil-images/mine/6vqn) | Co-crystal structure of human PD-L1 complexed with Compound A | 分子名称: | N,N'-(2,2'-dimethyl[1,1'-biphenyl]-3,3'-diyl)bis(5-{[(2-hydroxyethyl)amino]methyl}pyridine-2-carboxamide), Programmed cell death 1 ligand 1 | 著者 | White, A, Lakshminarasimhan, D, Leo, C, Suto, R.K. | 登録日 | 2020-02-05 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1. Nat Commun, 12, 2021
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6VPY
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![BU of 6vpy by Molmil](/molmil-images/mine/6vpy) | I33M (I3.2 mutant from CH103 Lineage) | 分子名称: | CHLORIDE ION, GLYCEROL, I33M heavy chain, ... | 著者 | Fera, D, Zhou, J. | 登録日 | 2020-02-04 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | The Effects of Framework Mutations at the Variable Domain Interface on Antibody Affinity Maturation in an HIV-1 Broadly Neutralizing Antibody Lineage. Front Immunol, 11, 2020
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6XY2
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![BU of 6xy2 by Molmil](/molmil-images/mine/6xy2) | |
6LSA
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![BU of 6lsa by Molmil](/molmil-images/mine/6lsa) | Complex structure of bovine herpesvirus 1 glycoprotein D and bovine nectin-1 IgV | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... | 著者 | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | 登録日 | 2020-01-17 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | 主引用文献 | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor. Sci Adv, 6, 2020
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6TXZ
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![BU of 6txz by Molmil](/molmil-images/mine/6txz) | FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3 | 分子名称: | Fab H, Fab L, Hepatitis A virus cellular receptor 2 | 著者 | Musil, D, Sood, V. | 登録日 | 2020-01-15 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology, 9, 2020
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6V8Z
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![BU of 6v8z by Molmil](/molmil-images/mine/6v8z) | |
6V8X
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![BU of 6v8x by Molmil](/molmil-images/mine/6v8x) | VRC01 Bound BG505 F14 HIV-1 SOSIP Envelope Trimer Structure | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Henderson, R, Acharya, P. | 登録日 | 2019-12-12 | 公開日 | 2020-02-05 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements. Nat Commun, 11, 2020
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6V80
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![BU of 6v80 by Molmil](/molmil-images/mine/6v80) | |
6LHF
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![BU of 6lhf by Molmil](/molmil-images/mine/6lhf) | Crystal structure of chicken cCD8aa/pBF2*15:01 | 分子名称: | Beta-2-microglobulin, CD8 alpha chain, MHC class I, ... | 著者 | Liu, Y.J, Xia, C. | 登録日 | 2019-12-08 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Combination of CD8 alpha alpha and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken gamma delta T Cells Response. Front Immunol, 11, 2020
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6LHG
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![BU of 6lhg by Molmil](/molmil-images/mine/6lhg) | Crystal structure of chicken cCD8aa/pBF2*04:01 | 分子名称: | Beta-2-microglobulin, CD8 alpha chain, IE8 peptide, ... | 著者 | Liu, Y.J, Xia, C. | 登録日 | 2019-12-08 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The Combination of CD8 alpha alpha and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken gamma delta T Cells Response. Front Immunol, 11, 2020
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