6V8X

VRC01 Bound BG505 F14 HIV-1 SOSIP Envelope Trimer Structure

Summary for 6V8X

Entry DOI	10.2210/pdb6v8x/pdb
EMDB information	21111 21112
Descriptor	Envelope glycoprotein gp120, Envelope glycoprotein gp41, VRC01 Fab Heavy Chain, ... (8 entities in total)
Functional Keywords	trimer, complex, immunogen, hiv-1, viral protein-immune system complex, viral protein/immune system
Biological source	Human immunodeficiency virus 1 (HIV-1) More
Total number of polymer chains	12
Total formula weight	371127.75
Authors	Henderson, R.,Acharya, P. (deposition date: 2019-12-12, release date: 2020-02-05, Last modification date: 2020-07-29)
Primary citation	Henderson, R.,Lu, M.,Zhou, Y.,Mu, Z.,Parks, R.,Han, Q.,Hsu, A.L.,Carter, E.,Blanchard, S.C.,Edwards, R.J.,Wiehe, K.,Saunders, K.O.,Borgnia, M.J.,Bartesaghi, A.,Mothes, W.,Haynes, B.F.,Acharya, P.,Munir Alam, S. Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements. Nat Commun, 11:520-520, 2020 Cited by PubMed: 31980614 DOI: 10.1038/s41467-019-14196-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation