6VRH
Cryo-EM structure of the wild-type human serotonin transporter complexed with paroxetine and 8B6 Fab
Summary for 6VRH
| Entry DOI | 10.2210/pdb6vrh/pdb |
| EMDB information | 21368 21369 21370 |
| Descriptor | Sodium-dependent serotonin transporter, 8B6 antibody, light chain, 8B6 antibody, heavy chain, ... (7 entities in total) |
| Functional Keywords | antidepressant, complex, transporter, antibody, transport protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 119095.74 |
| Authors | Coleman, J.A.,Navratna, V.,Yang, D. (deposition date: 2020-02-07, release date: 2020-03-11, Last modification date: 2020-09-23) |
| Primary citation | Coleman, J.A.,Navratna, V.,Antermite, D.,Yang, D.,Bull, J.A.,Gouaux, E. Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9:-, 2020 Cited by PubMed: 32618269DOI: 10.7554/eLife.56427 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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