6TXZ
FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3
Summary for 6TXZ
Entry DOI | 10.2210/pdb6txz/pdb |
Descriptor | Hepatitis A virus cellular receptor 2, Fab H, Fab L (3 entities in total) |
Functional Keywords | fab, antibody, tim3, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 236808.41 |
Authors | |
Primary citation | Zhang, D.,Jiang, F.,Zaynagetdinov, R.,Huang, H.,Sood, V.D.,Wang, H.,Zhao, X.,Jenkins, M.H.,Ji, Q.,Wang, Y.,Nannemann, D.P.,Musil, D.,Wesolowski, J.,Paoletti, A.,Bartholomew, T.,Derner, M.G.,An, Q.,Iffland, C.,Halle, J.P. Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology, 9:1744921-1744921, 2020 Cited by PubMed: 32313722DOI: 10.1080/2162402X.2020.1744921 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.06 Å) |
Structure validation
Download full validation report