6D32
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![BU of 6d32 by Molmil](/molmil-images/mine/6d32) | Crystal structure of Xenopus Smoothened in complex with cyclopamine | 分子名称: | Cyclopamine, Smoothened,Soluble cytochrome b562,Smoothened | 著者 | Huang, P, Zheng, S, Kim, Y, Kruse, A.C, Salic, A. | 登録日 | 2018-04-14 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.751 Å) | 主引用文献 | Structural Basis of Smoothened Activation in Hedgehog Signaling. Cell, 174, 2018
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7W0O
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![BU of 7w0o by Molmil](/molmil-images/mine/7w0o) | Cryo-EM structure of a monomeric GPCR-Gi complex with peptide | 分子名称: | Apelin receptor early endogenous ligand, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, F, Yue, Y, Liu, L.E, Wu, L.J, Hanson, M. | 登録日 | 2021-11-18 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structural insight into apelin receptor-G protein stoichiometry. Nat.Struct.Mol.Biol., 29, 2022
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8XV9
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![BU of 8xv9 by Molmil](/molmil-images/mine/8xv9) | Fedratinib-bound human SLC19A3 | 分子名称: | N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide, Soluble cytochrome b562,Thiamine transporter 2 | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | 登録日 | 2024-01-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34, 2024
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7TX7
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7EZC
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![BU of 7ezc by Molmil](/molmil-images/mine/7ezc) | Adenosine A2a receptor mutant-I92N | 分子名称: | 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide, Adenosine receptor A2a,Soluble cytochrome b562 | 著者 | Cui, M, Zhou, Q, Yao, D, Zhao, S, Song, G. | 登録日 | 2021-06-01 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structure of a constitutive active mutant of adenosine A 2A receptor. Iucrj, 9, 2022
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6USF
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![BU of 6usf by Molmil](/molmil-images/mine/6usf) | CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor with varenicline in complex with anti-BRIL synthetic antibody BAK5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, ... | 著者 | Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A. | 登録日 | 2019-10-26 | 公開日 | 2020-04-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nat Commun, 11, 2020
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7BW0
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![BU of 7bw0 by Molmil](/molmil-images/mine/7bw0) | Active human TGR5 complex with a synthetic agonist 23H | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Chen, G, Wang, X.K, Chen, Q, Hu, H.L, Ren, R.B. | 登録日 | 2020-04-12 | 公開日 | 2020-09-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of activated bile acids receptor TGR5 in complex with stimulatory G protein. Signal Transduct Target Ther, 5, 2020
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6D35
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![BU of 6d35 by Molmil](/molmil-images/mine/6d35) | Crystal structure of Xenopus Smoothened in complex with cholesterol | 分子名称: | CHOLESTEROL, Smoothened,Soluble cytochrome b562,Smoothened | 著者 | Huang, P, Zheng, S, Kim, Y, Kruse, A.C, Salic, A. | 登録日 | 2018-04-14 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structural Basis of Smoothened Activation in Hedgehog Signaling. Cell, 174, 2018
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8F7C
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8DRA
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![BU of 8dra by Molmil](/molmil-images/mine/8dra) | LRRC8A:C conformation 2 (oblong) LRR mask | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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5NJ6
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![BU of 5nj6 by Molmil](/molmil-images/mine/5nj6) | Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in ternary complex with Fab3949 and AZ7188 at 4.0 angstrom resolution | 分子名称: | Fab3949 H, Fab3949 L, Proteinase-activated receptor 2,Soluble cytochrome b562,Proteinase-activated receptor 2 | 著者 | Cheng, R.K.Y, Fiez-Vandal, C, Schlenker, O, Edman, K, Aggeler, B, Brown, D.G, Brown, G, Cooke, R.M, Dumelin, C.E, Dore, A.S, Geschwindner, S, Grebner, C, Hermansson, N.-O, Jazayeri, A, Johansson, P, Leong, L, Prihandoko, R, Rappas, M, Soutter, H, Snijder, A, Sundstrom, L, Tehan, B, Thornton, P, Troast, D, Wiggin, G, Zhukov, A, Marshall, F.H, Dekker, N. | 登録日 | 2017-03-28 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural insight into allosteric modulation of protease-activated receptor 2. Nature, 545, 2017
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8DRO
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![BU of 8dro by Molmil](/molmil-images/mine/8dro) | LRRC8A:C conformation 1 (round) LRR focus 2 | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DRN
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![BU of 8drn by Molmil](/molmil-images/mine/8drn) | LRRC8A:C conformation 1 (round) LRR focus 1 | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8F7E
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![BU of 8f7e by Molmil](/molmil-images/mine/8f7e) | LRRC8A(T48D):C conformation 2 top focus | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-11-18 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DRQ
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![BU of 8drq by Molmil](/molmil-images/mine/8drq) | LRRC8A:C conformation 1 (round) LRR focus 3 | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8F7D
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![BU of 8f7d by Molmil](/molmil-images/mine/8f7d) | LRRC8A(T48D):C conformation 2 top focus | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-11-18 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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6MH8
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![BU of 6mh8 by Molmil](/molmil-images/mine/6mh8) | High-viscosity injector-based Pink Beam Serial Crystallography of Micro-crystals at a Synchrotron Radiation Source | 分子名称: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a, Soluble cytochrome b562 chimeric construct | 著者 | Martin-Garcia, J.M, Zhu, L, Mendez, D, Lee, M, Chun, E, Li, C, Hu, H, Subramanian, G, Kissick, D, Ogata, C, Henning, R, Ishchenko, A, Dobson, Z, Zhan, S, Weierstall, U, Spence, J.C.H, Fromme, P, Zatsepin, N.A, Fischetti, R.F, Cherezov, V, Liu, W. | 登録日 | 2018-09-17 | 公開日 | 2019-04-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source. Iucrj, 6, 2019
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7W0N
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![BU of 7w0n by Molmil](/molmil-images/mine/7w0n) | Cryo-EM structure of a dimeric GPCR-Gi complex with peptide | 分子名称: | Apelin receptor early endogenous ligand, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, F, Yue, Y, Wu, L.J, Liu, L.E, Hanson, M. | 登録日 | 2021-11-18 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (4.21 Å) | 主引用文献 | Structural insight into apelin receptor-G protein stoichiometry. Nat.Struct.Mol.Biol., 29, 2022
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8F7J
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![BU of 8f7j by Molmil](/molmil-images/mine/8f7j) | LRRC8A(T48D):C conformation 2 top focus | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-11-18 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.32 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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6CMO
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![BU of 6cmo by Molmil](/molmil-images/mine/6cmo) | Rhodopsin-Gi complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab light chain, ... | 著者 | Kang, Y, Kuybeda, O, de Waal, P.W, Mukherjee, S, Van Eps, N, Dutka, P, Zhou, X.E, Bartesaghi, A, Erramilli, S, Morizumi, T, Gu, X, Yin, Y, Liu, P, Jiang, Y, Meng, X, Zhao, G, Melcher, K, Earnst, O.P, Kossiakoff, A.A, Subramaniam, S, Xu, H.E. | 登録日 | 2018-03-05 | 公開日 | 2018-06-20 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structure of human rhodopsin bound to an inhibitory G protein. Nature, 558, 2018
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1APC
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1QPU
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![BU of 1qpu by Molmil](/molmil-images/mine/1qpu) | SOLUTION STRUCTURE OF OXIDIZED ESCHERICHIA COLI CYTOCHROME B562 | 分子名称: | CYTOCHROME B562, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Arnesano, F, Banci, L, Bertini, I, Faraone-Mennella, J, Rosato, A, Barker, P.D, Fersht, A.R. | 登録日 | 1999-05-30 | 公開日 | 1999-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of oxidized Escherichia coli cytochrome b562. Biochemistry, 38, 1999
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1QQ3
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![BU of 1qq3 by Molmil](/molmil-images/mine/1qq3) | THE SOLUTION STRUCTURE OF THE HEME BINDING VARIANT ARG98CYS OF OXIDIZED ESCHERICHIA COLI CYTOCHROME B562 | 分子名称: | CYTOCHROME B562, HEME B/C | 著者 | Arnesano, F, Banci, L, Bertini, I, Ciofi-Baffoni, S, Barker, P.D, Woodyear, T. | 登録日 | 1999-06-10 | 公開日 | 2000-05-24 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural consequences of b- to c-type heme conversion in oxidized Escherichia coli cytochrome b562. Biochemistry, 39, 2000
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