7EZC

Adenosine A2a receptor mutant-I92N

Summary for 7EZC

• Entry DOI: 10.2210/pdb7ezc/pdb
• Descriptor: Adenosine receptor A2a,Soluble cytochrome b562, 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide (2 entities in total)
• Functional Keywords: gpcr, adenosine, agonist, active mutation, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 97873.61

Authors

Cui, M.,Zhou, Q.,Yao, D.,Zhao, S.,Song, G. (deposition date: 2021-06-01, release date: 2022-04-13, Last modification date: 2023-11-29)

• Primary citation: Cui, M.,Zhou, Q.,Xu, Y.,Weng, Y.,Yao, D.,Zhao, S.,Song, G.; Crystal structure of a constitutive active mutant of adenosine A 2A receptor.; Iucrj, 9:333-341, 2022; PubMed: 35546802; DOI: 10.1107/S2052252522001907

Experimental method

X-RAY DIFFRACTION (3.8 Å)