8DRA
LRRC8A:C conformation 2 (oblong) LRR mask
Summary for 8DRA
| Entry DOI | 10.2210/pdb8dra/pdb |
| Related | 8DR8 |
| EMDB information | 27674 27675 |
| Descriptor | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C (2 entities in total) |
| Functional Keywords | ion channel, volume-regulation, membrane protein |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 3 |
| Total formula weight | 304684.80 |
| Authors | Kern, D.M.,Brohawn, S.G. (deposition date: 2022-07-20, release date: 2023-03-08, Last modification date: 2023-07-05) |
| Primary citation | Kern, D.M.,Bleier, J.,Mukherjee, S.,Hill, J.M.,Kossiakoff, A.A.,Isacoff, E.Y.,Brohawn, S.G. Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30:841-852, 2023 Cited by PubMed: 36928458DOI: 10.1038/s41594-023-00944-6 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.98 Å) |
Structure validation
Download full validation report
