7TX7
Cryo-EM structure of the human reduced folate carrier
Summary for 7TX7
Entry DOI | 10.2210/pdb7tx7/pdb |
EMDB information | 26155 26156 |
Descriptor | Reduced folate transporter,Soluble cytochrome b562, Digitonin (2 entities in total) |
Functional Keywords | membrane transporter, reduced folate carrier, slc19, slc19a1, transport protein, anion exchanger |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 79714.44 |
Authors | Wright, N.J.,Fedor, J.G.,Lee, S.-Y. (deposition date: 2022-02-07, release date: 2022-09-21, Last modification date: 2024-06-12) |
Primary citation | Wright, N.J.,Fedor, J.G.,Zhang, H.,Jeong, P.,Suo, Y.,Yoo, J.,Hong, J.,Im, W.,Lee, S.Y. Methotrexate recognition by the human reduced folate carrier SLC19A1. Nature, 609:1056-1062, 2022 Cited by PubMed: 36071163DOI: 10.1038/s41586-022-05168-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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