4DHZ
 
 | | The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub | | 分子名称: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-30 | | 公開日 | 2012-02-22 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
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4DDG
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4II2
 | | Crystal structure of Ubiquitin activating enzyme 1 (Uba1) in complex with the Ub E2 Ubc4, ubiquitin, and ATP/Mg | | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Olsen, S.K, Lima, C.D. | | 登録日 | 2012-12-19 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.
Mol.Cell, 49, 2013
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4JGH
 | | Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5 | | 分子名称: | Cullin-5, Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 1, ... | | 著者 | Kim, Y.K, Kwak, M.J, Ku, B, Suh, H.Y, Joo, K, Lee, J, Jung, J.U, Oh, B.H. | | 登録日 | 2013-03-01 | | 公開日 | 2013-08-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
Acta Crystallogr.,Sect.D, 69, 2013
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3PTF
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3A33
 | | UbcH5b~Ubiquitin Conjugate | | 分子名称: | GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 | | 著者 | Sakata, E, Satoh, T, Yamamoto, S, Yamaguchi, Y, Yagi-Utsumi, M, Kurimoto, E, Wakatsuki, S, Kato, K. | | 登録日 | 2009-06-08 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of UbcH5b~Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2~Ub Conjugates
Structure, 18, 2010
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2EKE
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2C9W
 | | CRYSTAL STRUCTURE OF SOCS-2 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 1.9A RESOLUTION | | 分子名称: | NICKEL (II) ION, SULFATE ION, SUPPRESSOR OF CYTOKINE SIGNALING 2, ... | | 著者 | Debreczeni, J.E, Bullock, A, Amos, A, Savitsky, P, Barr, A, Burgess, N, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S. | | 登録日 | 2005-12-14 | | 公開日 | 2006-02-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 103, 2006
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2FUH
 | | Solution Structure of the UbcH5c/Ub Non-covalent Complex | | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 D3 | | 著者 | Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E. | | 登録日 | 2006-01-26 | | 公開日 | 2006-03-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21, 2006
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3OJ4
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6AH0
 | | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | | 登録日 | 2018-08-15 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
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5EYA
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6AHD
 | | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | | 登録日 | 2018-08-17 | | 公開日 | 2018-11-14 | | 最終更新日 | 2021-06-30 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
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6AZ1
 | | Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin | | 分子名称: | E-site tRNA, LACK1, MAGNESIUM ION, ... | | 著者 | Shalev-Benami, M, Zhang, Y, Rozenberg, H, Matzov, D, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G. | | 登録日 | 2017-09-09 | | 公開日 | 2017-12-06 | | 最終更新日 | 2019-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
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5FER
 | | Complex of TRIM25 RING with UbcH5-Ub | | 分子名称: | E3 ubiquitin/ISG15 ligase TRIM25, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D1, ... | | 著者 | Rittinger, K, Koliopoulos, M.G, Esposito, D. | | 登録日 | 2015-12-17 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Embo J., 35, 2016
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5EDV
 | | Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex | | 分子名称: | E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... | | 著者 | Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J. | | 登録日 | 2015-10-22 | | 公開日 | 2016-01-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | | 主引用文献 | Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.
Nature, 529, 2016
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6C5X
 | | Crystal Structure of SOCS1 in complex with ElonginB and ElonginC | | 分子名称: | Elongin-B, Elongin-C, GP130 peptide fragment, ... | | 著者 | Kershaw, N.J, Laktyushin, A, Babon, J.J. | | 登録日 | 2018-01-17 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.105 Å) | | 主引用文献 | The molecular basis of JAK/STAT inhibition by SOCS1.
Nat Commun, 9, 2018
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5FLX
 | | Mammalian 40S HCV-IRES complex | | 分子名称: | 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... | | 著者 | Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. | | 登録日 | 2015-10-28 | | 公開日 | 2015-12-23 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
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6CP2
 | | SidC in complex with UbcH7~Ub | | 分子名称: | Polyubiquitin-B, SidC, Ubiquitin-conjugating enzyme E2 L3 | | 著者 | Wasilko, D.J, Huang, Q, Mao, Y. | | 登録日 | 2018-03-13 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Insights into the ubiquitin transfer cascade catalyzed by theLegionellaeffector SidC.
Elife, 7, 2018
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5GAK
 | | Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A | | 分子名称: | 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 5.8S rRNA, ... | | 著者 | Schmidt, C, Becker, T. | | 登録日 | 2015-12-09 | | 公開日 | 2016-02-24 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome.
Nucleic Acids Res., 44, 2016
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5GJQ
 | | Structure of the human 26S proteasome bound to USP14-UbAl | | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | | 著者 | Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G. | | 登録日 | 2016-07-01 | | 公開日 | 2016-08-17 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
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6D4P
 | | Ube2D1 in complex with ubiquitin variant Ubv.D1.1 | | 分子名称: | Ubiquitin Variant Ubv.D1.1, Ubiquitin-conjugating enzyme E2 D1 | | 著者 | Ceccarelli, D.F, Garg, P, Sidhu, S, Sicheri, F. | | 登録日 | 2018-04-18 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes.
J.Mol.Biol., 432, 2020
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5HPT
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5IFR
 | | Structure of the stable UBE2D3-UbDha conjugate | | 分子名称: | GLYCEROL, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D3 | | 著者 | Pruneda, J.N, Mulder, M.P.C, Witting, K, Ovaa, H, Komander, D. | | 登録日 | 2016-02-26 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Nat.Chem.Biol., 12, 2016
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5JNE
 | | E2-SUMO-Siz1 E3-SUMO-PCNA complex | | 分子名称: | E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ... | | 著者 | Lima, C.D, Streich Jr, F.C. | | 登録日 | 2016-04-29 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Capturing a substrate in an activated RING E3/E2-SUMO complex.
Nature, 536, 2016
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