5EDV
Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex
Summary for 5EDV
Entry DOI | 10.2210/pdb5edv/pdb |
Descriptor | E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 D2, Polyubiquitin-B, ... (4 entities in total) |
Functional Keywords | lubac, rbr, e3 ubiquitin ligase, e2, ligase-transferase complex, ligase/transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 9 |
Total formula weight | 173205.42 |
Authors | Lechtenberg, B.C.,Mace, P.D.,Sanishvili, R.,Riedl, S.J. (deposition date: 2015-10-22, release date: 2016-01-20, Last modification date: 2023-09-27) |
Primary citation | Lechtenberg, B.C.,Rajput, A.,Sanishvili, R.,Dobaczewska, M.K.,Ware, C.F.,Mace, P.D.,Riedl, S.J. Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation. Nature, 529:546-550, 2016 Cited by PubMed: 26789245DOI: 10.1038/nature16511 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.48 Å) |
Structure validation
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