5EYA

TRIM25 RING domain in complex with Ubc13-Ub conjugate

Summary for 5EYA

• Entry DOI: 10.2210/pdb5eya/pdb
• Related: 4LTB
• Descriptor: Ubiquitin-conjugating enzyme E2 N, Tripartite motif-containing 25 variant, Polyubiquitin-B, ... (5 entities in total)
• Functional Keywords: complex, e3 ligase, ubiquitination, signaling protein-transferase complex, signaling protein/transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 70792.72

Authors

Pornillos, O.,Sanchez, J.G. (deposition date: 2015-11-24, release date: 2016-08-17, Last modification date: 2019-12-25)

• Primary citation: Sanchez, J.G.,Chiang, J.J.,Sparrer, K.M.,Alam, S.L.,Chi, M.,Roganowicz, M.D.,Sankaran, B.,Gack, M.U.,Pornillos, O.; Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.; Cell Rep, 16:1315-1325, 2016; PubMed: 27425606; DOI: 10.1016/j.celrep.2016.06.070

Experimental method

X-RAY DIFFRACTION (2.4 Å)