6C5X

Crystal Structure of SOCS1 in complex with ElonginB and ElonginC

Summary for 6C5X

• Entry DOI: 10.2210/pdb6c5x/pdb
• Descriptor: Elongin-B, Elongin-C, Suppressor of Cytokine Signalling 1, ... (5 entities in total)
• Functional Keywords: complex, ubiquitination, cytokine signalling, socs, signaling protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q15370 Q15369
• Total number of polymer chains: 7
• Total formula weight: 87127.09

Authors

Kershaw, N.J.,Laktyushin, A.,Babon, J.J. (deposition date: 2018-01-17, release date: 2018-05-02, Last modification date: 2023-11-15)

• Primary citation: Liau, N.P.D.,Laktyushin, A.,Lucet, I.S.,Murphy, J.M.,Yao, S.,Whitlock, E.,Callaghan, K.,Nicola, N.A.,Kershaw, N.J.,Babon, J.J.; The molecular basis of JAK/STAT inhibition by SOCS1.; Nat Commun, 9:1558-1558, 2018; PubMed: 29674694; DOI: 10.1038/s41467-018-04013-1

Experimental method

X-RAY DIFFRACTION (3.105 Å)